Protein Alignment CCNG2 and CycA

DIOPT Version :10

• Sequence 1: NP_004345.1
• Gene: CCNG2 / 901
• HGNCID: 1593
• Length: 344
• Species: Homo sapiens
• Sequence 2: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 75/362 - (20%)
• Similarity: 126/362 - (34%)
• Gaps: 129/362 - (35%)

Human   140 DRFYTFICSVCS-SGPEYLKRLP---LQWVDIAHLCLYNLSVIHKKKY--------FDSELELMT 192
            |..:.||.:|.. .||.  |..|   ::.::|..|.||:|. .|.:||        .|::||:.:
  Fly    42 DLHHKFIEAVNQLGGPN--KATPKGLMKVMEIPGLTLYHLK-SHLQKYRLGKSMKFDDNKLEVSS 103

Human   193 YINENWDRLHPGELAD-----------TPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRI 246
             .:||.:.....:..|           .|..:|...:.|||.    |.|   |::||.|
  Fly   104 -ASENQEVESKNDSRDLRGCSVTEENSNPAKDRGLQITEALQ----MQM---EVQKKLH------ 154

Human   247 RVPPVPPNVAFKAEKEPEGTSHEFKIKGRKASKPTSDSREVSNGIEKKGKKKSVGRPPGPYTRKM 311
                                 .:.:::           |.:...||.:||          |.:.:
  Fly   155 ---------------------EQIEVQ-----------RHLQVKIEAQGK----------YLQSV 177

Human   312 IQKTAELPLDKESVSENPTLDLPCSIGRTE--GIAHSSN-----TSDVDLTGASSANE------- 362
            :.|.      :::::...:.:|.....|||  .:|...|     ||..:||......|
  Fly   178 LMKA------QQTLAGYSSSNLGMDFARTELSRLASMVNRGCPSTSFSELTQVEEEEEGFLWYKK 236

Human   363 TTSASISR-HCGLSDSRKRTRTGRSWPAAIPHLRRRRGRLPRRALQTQNSEVVKDDEGKEDYQFE 426
            ..:..||: .|.:..|...:.|..:......:|.:.. .||   |...||||:|   ||:
  Fly   237 PENRGISQLRCSVESSLTSSETSETKLDTDNNLNKSI-ELP---LMEINSEVMK---GKK----- 289

Human   427 ELNTEILNNLADQELQL----------NHLKNSITSY 453
                ..:|::...|..|          .|||.|:.:|
  Fly   290 ----RSINDVVCVEQPLMKRAFGVDDDEHLKLSLNTY 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNG2	NP_004345.1	CYCLIN_CCNG2	55..150	CDD:410287	3/9 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..320		2/18 (11%)
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	31/137 (23%)
		Cyclin_C	334..450	CDD:397230