DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCNG1 and CycB3

DIOPT Version :9

Sequence 1:NP_001350944.1 Gene:CCNG1 / 900 HGNCID:1592 Length:295 Species:Homo sapiens
Sequence 2:NP_001262934.1 Gene:CycB3 / 42971 FlyBaseID:FBgn0015625 Length:575 Species:Drosophila melanogaster


Alignment Length:350 Identity:67/350 - (19%)
Similarity:132/350 - (37%) Gaps:95/350 - (27%)


- Green bases have known domain annotations that are detailed below.


Human     2 IEVLTTTDSQKL------LHQLNALLEQESRCQPKVCGLRLIESAHD------------------ 42
            :|.:::.||.:|      ..:.:|.|:|::..||:...|.|.|:|..                  
  Fly   230 LEDVSSCDSMRLSGNFEAARRRSAKLQQKTEQQPQPLLLTLPETAPSQVVPIPPVPEEVEDFDRK 294

Human    43 ---------------------------------NGLRMTARLRDFEVKDLLSLTQFFGFDTETFS 74
                                             ..:.:|..:|...|..::.:.:.|..:.||..
  Fly   295 NWDDPFQVSHYAMDIFNYLKVREAEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETLY 359

Human    75 LAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139
            |||.::|.:|.:..:..:.|..:|.:.|::|.|  .:||..||..|.:.|....:...:|:|||:
  Fly   360 LAVKIVDLYLCREVINKEKLQLLGAAAFFIACK--YDERQPPLIEDFLYICDGAYNHDELVRMER 422

Human   140 IVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKAC-HCRIIFSKAKPSVL 203
            ..|..:.:.:....:::||:.|....:..:|     ::...|...:|... :..|.||.::.:..
  Fly   423 ETLRVIKYDLGIPLSYRFLRRYARCAKVPMP-----TLTLARYILELSLMDYANISFSDSQMASA 482

Human   204 ALSIIALEIQAQKCVELTEGIECLQKHS------KINGRDLTFWQELVSKCLTEYSSNKCSKPNV 262
            || .:||.:..        |...|.|.:      ...|..|..:.|:|    |..::....||..
  Fly   483 AL-FMALRMHG--------GPGQLDKQTWTSTLIYYTGYQLADFAEIV----TALNAGLHRKPRA 534

Human   263 QKLKWIVSGRTARQLKHSY-YRITH 286
                      |.:.:::.| ::|.|
  Fly   535 ----------TIKTIRNKYSHKIFH 549

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCNG1NP_001350944.1 CYCLIN_CCNG1 51..148 CDD:410286 26/96 (27%)
CycB3NP_001262934.1 Cyclin_N 308..433 CDD:278560 27/126 (21%)
Cyclin_C 435..555 CDD:281044 26/142 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5024
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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