Protein Alignment RHOT2 and Rhot2

DIOPT Version :10

• Sequence 1: NP_001339204.1
• Gene: RHOT2 / 89941
• HGNCID: 21169
• Length: 619
• Species: Homo sapiens
• Sequence 2: NP_861544.1
• Gene: Rhot2 / 287156
• RGDID: 727970
• Length: 622
• Species: Rattus norvegicus
• Alignment Length: 623
• Identity: 524/623 - (84%)
• Similarity: 559/623 - (89%)
• Gaps: 5/623 - (0%)

Human     1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQTD 65
            ||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||:
  Rat     1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTE 65

Human    66 EELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRSGSSMEA 130
            |||:||||||||||||||||||||||||||||||||||.|..|||:||||||||||||.||::||
  Rat    66 EELQEEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTIEA 130

Human   131 VLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRL 195
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 VLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRL 195

Human   196 SDQDLDQALSDEELNAFQQKSCFGHPLAPQALEDVKTVVCRNVAGGVREDRLTLDGFLFLNTLFI 260
            ||||||.||||:||||| ||||||||||||||||||.|||:||||||::|||||:||||||||||
  Rat   196 SDQDLDHALSDKELNAF-QKSCFGHPLAPQALEDVKRVVCKNVAGGVQDDRLTLEGFLFLNTLFI 259

Human   261 QRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTELNHLGYQFVQRVFEKHDQDRDGAL 325
            |||||||||||||||||||:||||.|||.|.::|||||||||||.|||||||||||||||.||.|
  Rat   260 QRGRHETTWTILRRFGYSDSLELTPDYLCPPLYVPPGCSTELNHRGYQFVQRVFEKHDQDHDGVL 324

Human   326 SPVELQSLFSVFPAAPWGPELPRTVRTEAGRLPLHGYLCQWTLVTYLDVRSCLGHLGYLGYPTLC 390
            ||.||:||||||..|||||||..||.||||.|.|.||||||||||||||:.||.|||||||||||
  Rat   325 SPTELESLFSVFSVAPWGPELLHTVPTEAGCLSLRGYLCQWTLVTYLDVQHCLAHLGYLGYPTLC 389

Human   391 EQD-QAHAITVTREKRLDQEKGQTQRSVLLCKVVGARGVGKSAFLQAFLGRGLGHQDTREQP--- 451
            ||| ||.||||||||||||||||||||||:|||:||||||||||||||||..||....|:.|
  Rat   390 EQDSQAQAITVTREKRLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGHSLGEARDRDAPEKL 454

Human   452 PGYAIDTVQVNGQEKYLILCEVGTDGLLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDG 516
            |.:.|:||:|:|||||||||||..|.||.||||.||||||||||.|||::|..||::||.:||||
  Rat   455 PTHTINTVRVSGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPETFVQCATIYKRYYMDG 519

Human   517 QTPCLFVSSKADLPEGVAVSGPSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLV 581
            ||||||:|||||||||||..|.|||||||:||||||..|||.|||:.|..:||||||||.||||.
  Rat   520 QTPCLFISSKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAQSSIDVFTQLATMATFPHLA 584

Human   582 HAELHPSSFWLRGLLGVVGAAVAAVLSFSLYRVLVKSQ 619
            |.||||:.|||||:|..||.|||||||||||||||||:
  Rat   585 HTELHPTPFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOT2	NP_001339204.1	Miro1	3..169	CDD:206680	154/165 (93%)
		EF_assoc_2	221..304	CDD:462444	71/82 (87%)
		EF_assoc_1	342..409	CDD:462443	56/67 (84%)
		Miro2	414..590	CDD:206679	128/178 (72%)
Rhot2	NP_861544.1	Miro1	3..169	CDD:206680	154/165 (93%)
		EF_assoc_2	220..303	CDD:462444	71/82 (87%)
		FRQ1	<307..>340	CDD:444056	26/32 (81%)
		EF_assoc_1	341..409	CDD:462443	56/67 (84%)
		Miro2	414..593	CDD:206679	128/178 (72%)