Protein Alignment RHOT2 and Rhot2

DIOPT Version :10

• Sequence 1: NP_001339204.1
• Gene: RHOT2 / 89941
• HGNCID: 21169
• Length: 619
• Species: Homo sapiens
• Sequence 2: NP_666111.1
• Gene: Rhot2 / 214952
• MGIID: 2384892
• Length: 620
• Species: Mus musculus
• Alignment Length: 621
• Identity: 527/621 - (84%)
• Similarity: 562/621 - (90%)
• Gaps: 3/621 - (0%)

Human     1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSEAEQTD 65
            ||||||||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||:
Mouse     1 MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTE 65

Human    66 EELREEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGGTTQGPRVPIILVGNKSDLRSGSSMEA 130
            |||:||||||||||||||||||.|||||||||||||||.|..|||:||||||||||||.||:|||
Mouse    66 EELQEEIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTMEA 130

Human   131 VLPIMSQFPEIETCVECSAKNLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRL 195
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 VLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRL 195

Human   196 SDQDLDQALSDEELNAFQQKSCFGHPLAPQALEDVKTVVCRNVAGGVREDRLTLDGFLFLNTLFI 260
            ||||.|..||||||||| ||||||||||||||||||.|||:||:|||:.|||||:||||||||||
Mouse   196 SDQDRDHGLSDEELNAF-QKSCFGHPLAPQALEDVKRVVCKNVSGGVQNDRLTLEGFLFLNTLFI 259

Human   261 QRGRHETTWTILRRFGYSDALELTADYLSPLIHVPPGCSTELNHLGYQFVQRVFEKHDQDRDGAL 325
            |||||||||||||||||||:||||.|||.|.:||||||||||||.|||||||:|||||||.||.|
Mouse   260 QRGRHETTWTILRRFGYSDSLELTPDYLYPALHVPPGCSTELNHRGYQFVQRMFEKHDQDHDGVL 324

Human   326 SPVELQSLFSVFPAAPWGPELPRTVRTEAGRLPLHGYLCQWTLVTYLDVRSCLGHLGYLGYPTLC 390
            ||.|||:|||||..|||||||..||.|:||.||||||||||||:|||||:.||.|||||||||||
Mouse   325 SPTELQNLFSVFSGAPWGPELLHTVPTQAGCLPLHGYLCQWTLMTYLDVQQCLAHLGYLGYPTLC 389

Human   391 EQD-QAHAITVTREKRLDQEKGQTQRSVLLCKVVGARGVGKSAFLQAFLGRGLGH-QDTREQPPG 453
            ||| ||.||||||||:|||||||||||||:|||:||||||||||||||||..||. :|..|:.|.
Mouse   390 EQDSQAQAITVTREKKLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGNSLGEARDPPEKFPL 454

Human   454 YAIDTVQVNGQEKYLILCEVGTDGLLATSLDATCDVACLMFDGSDPKSFAHCASVYKHHYMDGQT 518
            :.|:||:|||||||||||||..|.||.||||.||||||||||.||||:|.|||::||.:||||||
Mouse   455 HTINTVRVNGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPKTFVHCATIYKRYYMDGQT 519

Human   519 PCLFVSSKADLPEGVAVSGPSPAEFCRKHRLPAPVPFSCAGPAEPSTTIFTQLATMAAFPHLVHA 583
            ||||::||||||||||..|.|||||||:||||||..|||.|||.|||.:||||||||.||||||.
Mouse   520 PCLFIASKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAMPSTDVFTQLATMATFPHLVHT 584

Human   584 ELHPSSFWLRGLLGVVGAAVAAVLSFSLYRVLVKSQ 619
            ||||:||||||:|..||.|||||||||||||||||:
Mouse   585 ELHPTSFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOT2	NP_001339204.1	Miro1	3..169	CDD:206680	154/165 (93%)
		EF_assoc_2	221..304	CDD:462444	71/82 (87%)
		EF_assoc_1	342..409	CDD:462443	55/67 (82%)
		Miro2	414..590	CDD:206679	133/176 (76%)
Rhot2	NP_666111.1	Miro1	3..169	CDD:206680	154/165 (93%)
		EF_assoc_2	220..303	CDD:462444	71/82 (87%)
		FRQ1	<307..>336	CDD:444056	23/28 (82%)
		EF_assoc_1	341..409	CDD:462443	55/67 (82%)
		Miro2	414..591	CDD:206679	133/176 (76%)