DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGLYRP1 and PGRP-LF

DIOPT Version :9

Sequence 1:	NP_005082.1	Gene:	PGLYRP1 / 8993	HGNCID:	8904	Length:	196	Species:	Homo sapiens
Sequence 2:	NP_648299.3	Gene:	PGRP-LF / 39064	FlyBaseID:	FBgn0035977	Length:	369	Species:	Drosophila melanogaster

Alignment Length:	201	Identity:	70/201 - (34%)
Similarity:	109/201 - (54%)	Gaps:	13/201 - (6%)

- Green bases have known domain annotations that are detailed below.

Human     4 RSMLLAWALPSLLRLGAAQ---------ETEDPACCSPIVPRNEWKA-LASECAQHLSLPLRYVV 58
            |..||.:.:..|:.:|.|.         .|..|.....|:.|:||.. ..|....||.||:..::
  Fly    21 RFELLYFCVILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNII 85

Human    59 VSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAH-SGHLW 122
            :.|||...|.....|..:.:.:|.:|||:.||.|:|||||:|.||.:|.||||:..|.| :|  :
  Fly    86 IHHTATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNG--Y 148

Human   123 NPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLI 187
            ..:|:.|:|:|.:::..|..:.|.||:.|:..||....|:.:|.:..||.:..|.|||.:|:.|:
  Fly   149 GAISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELM 213

Human   188 QNWPHY 193
            ||||.:
  Fly   214 QNWPRF 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGLYRP1	NP_005082.1	PGRP	31..173	CDD:128941	52/143 (36%)
PGRP-LF	NP_648299.3	PGRP	57..199	CDD:128941	52/143 (36%)
PGRP-LF	NP_648299.3	PGRP	236..363	CDD:295442
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5479
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6354
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.700