DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGLYRP1 and PGRP-SC2

DIOPT Version :9

Sequence 1:	NP_005082.1	Gene:	PGLYRP1 / 8993	HGNCID:	8904	Length:	196	Species:	Homo sapiens
Sequence 2:	NP_610410.1	Gene:	PGRP-SC2 / 35862	FlyBaseID:	FBgn0043575	Length:	184	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	77/163 - (47%)
Similarity:	108/163 - (66%)	Gaps:	1/163 - (0%)

- Green bases have known domain annotations that are detailed below.

Human    33 IVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPASCQQQARNVQHYHMKTLGWCDVGYNF 97
            |:.::||...::.....|:..|.|.|:.||||:.|:|.|:|..|.:|:|.|||.:|||.|:||||
  Fly    23 IISKSEWGGRSATSKTSLANYLSYAVIHHTAGNYCSTKAACITQLQNIQAYHMDSLGWADIGYNF 87

Human    98 LIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMDRVPTPQAIRAAQGLLACGVAQGALR 162
            |||.||.||||||||..|||:.: ||..||||||:|||.....|...|.||:|||:..|::|.:.
  Fly    88 LIGGDGNVYEGRGWNVMGAHATN-WNSKSIGISFLGNYNTNTLTSAQITAAKGLLSDAVSRGQIV 151

Human   163 SNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRS 195
            |.|:|.|||.|..|..||..:::.|:.|.::::
  Fly   152 SGYILYGHRQVGSTECPGTNIWNEIRTWSNWKA 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGLYRP1	NP_005082.1	PGRP	31..173	CDD:128941	71/139 (51%)
PGRP-SC2	NP_610410.1	PGRP	21..162	CDD:128941	71/139 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152331
Domainoid	1	1.000	147	1.000	Domainoid score	I4515
eggNOG	1	0.900	-	-		E1_COG5479
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4200
Isobase	1	0.950	-	0	Normalized mean entropy	S6354
OMA	1	1.010	-	-		QHG46811
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	1	1.000	-	-		mtm8604
orthoMCL	1	0.900	-	-		OOG6_101717
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4719
SonicParanoid	1	1.000	-	-		X1649
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.650