DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGLYRP1 and PGRP-SA

DIOPT Version :9

Sequence 1:	NP_005082.1	Gene:	PGLYRP1 / 8993	HGNCID:	8904	Length:	196	Species:	Homo sapiens
Sequence 2:	NP_001285128.1	Gene:	PGRP-SA / 32099	FlyBaseID:	FBgn0030310	Length:	203	Species:	Drosophila melanogaster

Alignment Length:	188	Identity:	76/188 - (40%)
Similarity:	110/188 - (58%)	Gaps:	2/188 - (1%)

- Green bases have known domain annotations that are detailed below.

Human     8 LAWALPSLLRLGAAQETEDPACCSPIVPRNEWKALASECAQHLSLPLRYVVVSHTAGSSCNTPAS 72
            |...|.:.:..|.::: ..||.|..|..:.:|....|....:...|:||||:.||....|:....
  Fly    16 LVLLLLAFVSAGKSRQ-RSPANCPTIKLKRQWGGKPSLGLHYQVRPIRYVVIHHTVTGECSGLLK 79

Human    73 CQQQARNVQHYHMKTLGWCDVGYNFLIGEDGLVYEGRGWNFTGAHSGHLWNPMSIGISFMGNYMD 137
            |.:..:|:|.||...|.:.|:.||||||.||:||||.||...|||: :.:|.:..||:|:||::|
  Fly    80 CAEILQNMQAYHQNELDFNDISYNFLIGNDGIVYEGTGWGLRGAHT-YGYNAIGTGIAFIGNFVD 143

Human   138 RVPTPQAIRAAQGLLACGVAQGALRSNYVLKGHRDVQRTLSPGNQLYHLIQNWPHYRS 195
            ::|:..|::||:.||||||.||.|..:|.|.....|..|.|||..||:.||.|||:.|
  Fly   144 KLPSDAALQAAKDLLACGVQQGELSEDYALIAGSQVISTQSPGLTLYNEIQEWPHWLS 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGLYRP1	NP_005082.1	PGRP	31..173	CDD:128941	57/141 (40%)
PGRP-SA	NP_001285128.1	PGRP	38..179	CDD:128941	57/141 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152332
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5479
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46811
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	1	1.000	-	-		otm41991
orthoMCL	1	0.900	-	-		OOG6_101717
Panther	1	1.100	-	-	O	PTHR11022
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1649
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.720