DRSC/TRiP Functional Genomics Resources

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Protein Alignment HSPB3 and hspb3

DIOPT Version :10

Sequence 1:NP_006299.1 Gene:HSPB3 / 8988 HGNCID:5248 Length:150 Species:Homo sapiens
Sequence 2:XP_002941074.1 Gene:hspb3 / 100135387 XenbaseID:XB-GENE-969539 Length:145 Species:Xenopus tropicalis


Alignment Length:148 Identity:83/148 - (56%)
Similarity:100/148 - (67%) Gaps:8/148 - (5%)


- Green bases have known domain annotations that are detailed below.


Human     1 MAKIILRHLIEIPVRYQEEFEARGLEDCRLDHALYALPGPTIVDLRKTRAAQSPPVDSAAETPPR 65
            |.::.:||.||.||||:|....|.|:||.|.|.|:|||||...|.:|....|   :|...|...:
 Frog     1 MQQVSIRHWIETPVRYKEMLATRDLQDCSLHHMLFALPGPQCSDHKKREDGQ---LDDQQEEDDK 62

Human    66 EGKSHFQILLDVVQFLPEDIIIQTFEGWLLIKAQHGTRMDEHGFISRSFTRQYKLPDGVEIKDLS 130
                 |::|||||||.|||||||.|||||:||.:||.||||||||||||||.|:||:|:.:.|||
 Frog    63 -----FKVLLDVVQFRPEDIIIQVFEGWLIIKGEHGCRMDEHGFISRSFTRTYQLPNGIGLTDLS 122

Human   131 AVLCHDGILVVEVKDPVG 148
            |..||||||.||.|...|
 Frog   123 AFFCHDGILAVEGKQKQG 140

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HSPB3NP_006299.1 ACD_HspB3_Like 63..145 CDD:107232 54/81 (67%)
hspb3XP_002941074.1 alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins. 55..137 CDD:469641 55/86 (64%)

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