Protein Alignment MVB12B and Mvb12

DIOPT Version :10

• Sequence 1: XP_016870764.1
• Gene: MVB12B / 89853
• HGNCID: 23368
• Length: 337
• Species: Homo sapiens
• Sequence 2: NP_573268.1
• Gene: Mvb12 / 32791
• FlyBaseID: FBgn0030894
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 256
• Identity: 69/256 - (26%)
• Similarity: 109/256 - (42%)
• Gaps: 54/256 - (21%)

Human    30 STMPEVKDLSEALPETSMDPITGVGVVASRNRAPTGYDVVAQTAD-GVDADLWKD-GLFKSKVTR 92
            ||......:...||:..  |||.:.:|....|.|..:..:::|.| ..|||||:| .||..:.||
  Fly    40 STTNVFNSIMSFLPDNR--PITSLHIVEDFERCPKNFSAISRTYDQDSDADLWRDYSLFGRQNTR 102

Human    93 YLCFTRSFSKENSHLGNVLVD-MKLIDIKDTLPVGFIPIQETVDTQEVAFRKKRLCIKFIPRDST 156
            |||.::|     ..|...:|: :::|..|...|..|..:..|.|:.:.|:||::|..|...|.:.
  Fly   103 YLCLSKS-----EGLPEYVVETLQVISDKTPPPKEFSQVSRTADSDQKAWRKRQLIYKLSKRGTV 162

Human   157 EAAICDIRIMGRTKQAPPQYTFIGELNSMGIWYRMGRVPRNHDSSQPTTPSQSSAASTPAP--NL 219
            ..|:.||.:..:.|.||..:...|::|.:.|.|:...:|              ...|.|.|  .|
  Fly   163 TQAVTDIILCSKLKAAPDGFKLAGDINGVLICYKTSAIP--------------VRLSPPVPGGGL 213

Human   220 PRHISLTLPAT-----------FRGRNSTR----------TDYEYQHSNLYAISALPRSPP 259
            |      .|||           .:|:.::|          .|||...:| |.|::..|..|
  Fly   214 P------APATCEVEQALNRLNLQGQRNSRGPLPQPPTEHHDYEEIQAN-YQINSPQRPAP 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MVB12B	XP_016870764.1	DUF2464	48..254	CDD:463017	63/231 (27%)
Mvb12	NP_573268.1	DUF2464	56..334	CDD:463017	65/240 (27%)