DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chi3l1 and Cht10

DIOPT Version :9

Sequence 1:	NP_001296749.1	Gene:	Chi3l1 / 89824	RGDID:	620874	Length:	391	Species:	Rattus norvegicus
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	151/381 - (39%)
Similarity:	226/381 - (59%)	Gaps:	32/381 - (8%)

- Green bases have known domain annotations that are detailed below.

  Rat    28 SAYKLVCYYTNWSQYREGNGSCFPDALDHSLCTHIIYSFANISNNKL---STSEWNDV--TLYGM 87
            |.||::||:|||:.||:|.|...||.::..||||:||.||.:..::|   :...|.||  ..|..
  Fly   963 SHYKVICYFTNWAWYRKGIGRFTPDDINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTR 1027

  Rat    88 LNTLKTRNPRLKTLLSVGGWSFG-SERFSRIVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYP- 150
            :.:||::.  :|..|::|||:.. .:::||:|.:..:|..||:....|:..|||:||||.|.||
  Fly  1028 VTSLKSKG--IKVSLALGGWNDSQGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLDLDWEYPV 1090

  Rat   151 ---------GPKDKQHFTTLIKELKAEFTKEVQPGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHL 206
                     ..::|..||..::||...|    :|  ..|:||.|||..:..:|:|||:.|::::.
  Fly  1091 CWQTECNKGSTEEKDGFTAWVQELSEAF----RP--RGLMLSTAVSPSRKIIDAGYDIPQLSRYF 1149

  Rat   207 DFINLMTYDFHGTWRHTTGHHSPLFRGQQDTGPDRFSNVDYGVGYMLRLGAPTNKLVMGIPTFGK 271
            |:|.:|||||||.|...|||.:||:....|  ...:.||:|.:.|.:..|||:.|||||||.:|:
  Fly  1150 DWIAVMTYDFHGHWDKKTGHVAPLYHHPDD--DFEYFNVNYSINYWMEKGAPSQKLVMGIPLYGQ 1212

  Rat   272 SFTLASSENQ-VGAPITGSGLPGRYTKEKGTLAYYEICDFL--RGAE-VHRILGQQVPFATKGNQ 332
            ||||.::.:. :.|.....|..|.:|:..|.|||||||:.:  :|.: ||...|:..|:|.||.|
  Fly  1213 SFTLENTNSSGLNAKAPAPGEAGEFTRAAGFLAYYEICERVNRQGWQVVHDEFGRMGPYAYKGTQ 1277

  Rat   333 WVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVHFPLTNAIKEAL 388
            ||.||.|:.|:.|...:::.:|.|.||||:|||||:.. ||:.|| ||...|...|
  Fly  1278 WVSYDSPDMVRKKSLLVRSLKLGGGMVWALDLDDFKNR-CGNGVH-PLLTEIHNVL 1331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chi3l1	NP_001296749.1	Glyco_18	31..365	CDD:214753	137/353 (39%)
Chi3l1	NP_001296749.1	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	147/375 (39%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	137/353 (39%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	147/375 (39%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9066
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850