Protein Alignment CCNE1 and CycA

DIOPT Version :10

• Sequence 1: NP_001229.1
• Gene: CCNE1 / 898
• HGNCID: 1589
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 73/263 - (27%)
• Similarity: 132/263 - (50%)
• Gaps: 32/263 - (12%)

Human   115 EVWKIMLNKEKTYLRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMAT 179
            ::.:.....||.:.....::.:...:...||:||:|||:||.|.|||..||.||:..:.||:: :
  Fly   206 DILEYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFL-S 269

Human   180 QENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPL 244
            |..||::.|||:|.::::||||.||||||::.:|.::||.:.:..::|.||.:|:|.|.:.|...
  Fly   270 QMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTP 334

Human   245 TIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHFSS 309
            |...::|.|   |.|.|:.|.|             :.:.|.:.::..:|....:....:|...:|
  Fly   335 TAYVFINTY---AVLCDMPEKL-------------KYMTLYISELSLMEGETYLQYLPSLMSSAS 383

Human   310 SELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSLDLLDKAR 374
            ..|.:.:.|            |..:...:.|..:.||:..:.|.   .|...||:.:.:|..:|.
  Fly   384 VALARHILG------------MEMWTPRLEEITTYKLEDLKTVV---LHLCHTHKTAKELNTQAM 433

Human   375 AKK 377
            .:|
  Fly   434 REK 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNE1	NP_001229.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		CYCLIN_CCNE1_rpt1	103..239	CDD:410282	47/123 (38%)
		CYCLIN_CCNE1_rpt2	243..356	CDD:410284	19/112 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..410		73/263 (28%)
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	47/123 (38%)
		Cyclin_C	334..450	CDD:397230	25/134 (19%)