DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SIGLEC10 and LOC101884840

DIOPT Version :9

Sequence 1:	NP_149121.2	Gene:	SIGLEC10 / 89790	HGNCID:	15620	Length:	697	Species:	Homo sapiens
Sequence 2:	XP_021322151.1	Gene:	LOC101884840 / 101884840	-ID:	-	Length:	692	Species:	Danio rerio

Alignment Length:	231	Identity:	57/231 - (24%)
Similarity:	93/231 - (40%)	Gaps:	50/231 - (21%)

- Green bases have known domain annotations that are detailed below.

Human    25 VQESVMVPEGLCISVPCSFSYP-------RQDWTGSTPAYGYWFKAVTETTKGAPVATNHQSREV 82
            :.|...:|.. |:.:|||||..       |..|..:...|.|....|                :|
Zfish   332 IPEITALPRS-CVVIPCSFSVEHKYLTGLRVRWVNNNGGYMYHTDPV----------------DV 379

Human    83 EMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPD 147
            ..:.:||.:|.|:|.:.||:|.:.|.:..|...:.|:.|: ...:|:|.|...|:.:.|...:|.
Zfish   380 LDNFKGRTRLLGNPDERNCTLEMDDVRTHDNGPFCFQAEK-KEEKYSFNNSCVFIIMRASPDQPV 443

Human   148 V-YIPETLEPGQPVTVICVFNWAFEECP--PPSFSWTGAALSSQGTKPTTSH----------FSV 199
            : .:||.:|||..|||.|...   ..|.  ||..:|     |....:.|.||          .|.
Zfish   444 MSSVPEDIEPGTAVTVKCSVK---HTCSSHPPKITW-----SVPTVRETISHNPMGGGVWETVSK 500

Human   200 LSFTPRPQDHNTDLTCHVDF----SRKGVSAQRTVR 231
            :.|.|...:...::.|..:|    ::...||..:|:
Zfish   501 MKFIPTGYEEEDEIICSANFWGGKTQSNSSAPLSVK 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SIGLEC10	NP_149121.2	Ig	23..140	CDD:299845	30/121 (25%)
		IG_like	26..126	CDD:214653	26/106 (25%)
		IG_like	262..340	CDD:214653
		IGc2	269..330	CDD:197706
		IG_like	367..442	CDD:214653
		Ig	378..439	CDD:143165
LOC101884840	XP_021322151.1	Ig	1..>83	CDD:325142
		Ig	226..307	CDD:325142
		Ig	335..426	CDD:325142	26/108 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I12412
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12035
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X34
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.060