Protein Alignment P4HA2 and CG31371

DIOPT Version :9

• Sequence 1: NP_001136071.1
• Gene: P4HA2 / 8974
• HGNCID: 8547
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_733375.2
• Gene: CG31371 / 43626
• FlyBaseID: FBgn0051371
• Length: 507
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 134/523 - (25%)
• Similarity: 234/523 - (44%)
• Gaps: 71/523 - (13%)

Human     3 LWVSALLMAWFGVLSCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEA 67
            ||   ||..:..|.|...|.|......:..|:..|.:|:..|::||...|.:|.:|:...:.:|.
  Fly     8 LW---LLQLFLLVESVAGANFARGEEQLQALLDTETQLIDGLRDYIERLERQLEEIRRETSAIEE 69

Human    68 LTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGA 132
            :.|: ....|.|:.:|:|.:.::||..:.||.||..........|...||.::...|::||...:
  Fly    70 IHSQ-VDSVEEYMGNPLNVFGILKRFESVWPGLEQKANATLEMVFGERLSDRQLTLPSEEDYEES 133

Human   133 AKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLD 197
            ...|:.||..|.||..::|.|.:.|.|..:.:|..||..:.|    :.|:.....|:|..|::|.
  Fly   134 LNHLLHLQSVYELDSNSLSLGVVNGFKLGSSMSWGDCLEVAR----KSDFPVARFWLESALEKLP 194

Human   198 AGEEATTTKSQ---------VLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQ- 252
            :..| .:|:||         :|:......::.|:|.|||.....||.|.|.::......|..|:
  Fly   195 SASE-NSTESQRERESGRVHILEATLNIEYRAGELSRALATAEELLLLLPMNQGIQKAKRKIEKA 258

Human   253 LLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHH-- 315
            :.::|..|....:::|         ::.:....|:.:.|.:|||      .::|.....|::|
  Fly   259 MAKKELPKGRGQKSKA---------KKQISKSTEQLLIEEICRG------AKQQVTTGSRFNHCQ 308

Human   316 -GNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASY 379
             ...:|.||:.|.:.|.....|:||.::||::.:|...:.::...:      .|.| ||    ||
  Fly   309 LDGSSPWLLLQPSRLEPVSSDPYIVLHHDVLTPKESNELLQLIDEE------EDTK-GV----SY 362

Human   380 RVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKH 444
            :..|.|.|.:..   :.|::|    :.||     |:|::..:  .|:...|...::.:.....||
  Fly   363 QSLKLSKLAQKK---LGRISR----LLGL-----EILELDPW--TGRRHGHEHITKLEHSSELKH 413

Human   445 LGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSG---EGDYRTRHAACPV 506
                  ||..:..:.....|||.|||.|..|:...:|:.:.|......|   |.|||:..|.|||
  Fly   414 ------VARLMLNLQAPGMGGAVVFPQLELAVNVPRGSLLHWRTRFAGGSSSEWDYRSGQAICPV 472

Human   507 LVG 509
            |:|
  Fly   473 LLG 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P4HA2	NP_001136071.1	P4Ha_N	26..155	CDD:311993	35/128 (27%)
		TPR	207..240		12/41 (29%)
		P4Hc	346..519	CDD:214780	43/167 (26%)
CG31371	NP_733375.2	P4Ha_N	30..156	CDD:285528	35/126 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391515at2759
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020