DRSC/TRiP Functional Genomics Resources

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Protein Alignment P4HA2 and CG34041

DIOPT Version :10

Sequence 1:NP_004190.1 Gene:P4HA2 / 8974 HGNCID:8547 Length:535 Species:Homo sapiens
Sequence 2:NP_001034077.5 Gene:CG34041 / 3885583 FlyBaseID:FBgn0054041 Length:568 Species:Drosophila melanogaster


Alignment Length:333 Identity:59/333 - (17%)
Similarity:124/333 - (37%) Gaps:51/333 - (15%)


- Green bases have known domain annotations that are detailed below.


Human    32 DLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTD 96
            :::..::.:|:.|:.||...|.||..|......:.....:...|.....:.||.:|.|:..:.:|
  Fly   266 NILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLAIASSPVASYSLIHHMQSD 330

Human    97 WPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPG--TK 159
            |...:..:.:|.....:|:|...:::.||..|.......:.::.:.|.:....|:.|.:.|  ||
  Fly   331 WTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMTAQDIANGVILGTQTK 395

Human   160 Y-----------------QAMLSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGE--EATTT 205
            |                 :.::|:.||..:...:....||..:..|:...:..|::..  :....
  Fly   396 YISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWLNVAISMLESSAYWDPIVP 460

Human   206 KSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAEL 270
            .:.:...|:....:..:...|||.....|..:|.:          .||:..::..:.    ...|
  Fly   461 SADLYLKLAEVYVKQQNWTLALETVEFALKSNPRN----------AQLIRMQKRLSY----HILL 511

Human   271 ATPEGIYERPVDYLPERDVYESLCRGEGVKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDS 335
            ..|:.         |:.::       |......|:...|:|.|....|....|:||.|.|..:..
  Fly   512 GPPKS---------PKLNI-------ENNDYRLRKNGSLYCFYDTKIRTFYSLLAPIKAEVLFID 560

Human   336 PHIVRYYD 343
            |.::.|::
  Fly   561 PLVILYHE 568

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
P4HA2NP_004190.1 P4Ha_N 26..157 CDD:462433 24/124 (19%)
BamD 159..>272 CDD:443281 18/131 (14%)
TPR 207..240 6/32 (19%)
P4Hc 346..519 CDD:214780
CG34041NP_001034077.5 P4Ha_N 29..138 CDD:462433
P4Ha_N 260..391 CDD:462433 24/124 (19%)
LapB <435..>505 CDD:442196 11/79 (14%)
TPR repeat 452..491 CDD:276809 5/38 (13%)
Blue background indicates that the domain is not in the aligned region.

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