|
Human 14 LDSKWLKTDIQLAFTRDGLCG--LWNEMVKDGEIVYTGTESTQN--GELPPRKDDSVEPSGTKK- 73
||:|||:.|: :|..|:...| |||.:::|.|:|.:.|....| |:|....||.....|.::
Fly 79 LDAKWLRADL-IASLRNAADGAVLWNHLIQDCELVSSPTAPLLNARGQLSYLGDDGKHYCGAQQL 142
Human 74 ---------------------EDLNDKEKKDEEETPAPIYRA-------KSILDSWVWGKQPDVN 110
..|:......:..|.|...:| ..:|..|:|.:.|...
Fly 143 KCSCCQPEYCGPLSACNCDGCRPLDSDTAIKKLTTQAAAQQAAHLSQATDMVLSGWLWSQPPSQQ 207
Human 111 ELKECLSVLVKEQQALAVQSATTTLSALRLKQRLVILERYFIALNR------------------T 157
...:|...::.|.|.||:::|...|||..|:|:|.|.||||:||.| |
Fly 208 ARLDCQRSMISELQELALRAAGNCLSAQHLRQQLFIYERYFVALKRERERERKSTTSAQAVASVT 272
Human 158 VFQENVKVKWKSSGISLPPVDKKSSRPAGKGVEGLARVGSRAALSFAFAFLRRAWRSGEDADLCS 222
.....:.....::.:...|.::: |..|..|||||.:.|||:|:|||||||||||||.::||
Fly 273 TANTTIAATTANAAVESQPAEQQ----AEHGALGLARVATHAALNFSFAFLRRAWRSGEDTEMCS 333
Human 223 ELLQESLDALRALPEASLFDESTVSSVWLEVVERATRFLRSVVTGDVHGTPATKGPGSIPLQDQH 287
|||.|:|.:|:.||||:||:.:.|||:||||:||:.:|||.|..||..|...| .||.|:|
Fly 334 ELLSEALASLQELPEATLFEAAVVSSLWLEVMERSIKFLRLVALGDPMGNRCT-----APLNDRH 393
Human 288 LALAILLELAVQRGTLSQMLSAILLLLQLWDSGAQETDNERSAQGTSAPLLPLLQRFQSI-ICRK 351
.||.:||||.||:|||:..|..::|||.||:......||....:.|.|||..:|.|:|.| ...|
Fly 394 TALCLLLELGVQKGTLAATLECVVLLLLLWEKDRAGNDNRDMPRKTGAPLQRILLRYQKIGATAK 458
Human 352 DAPHSEGDMHLLSGPL-SPNESFLRYLTLPQDNELAIDLRQTAVVVMAHLDRLATPCMPPL---- 411
....:.|: ..|: |..|:|||:|:||:.:...:|||:.|||:::||||:..|.||..
Fly 459 GGGIAGGE----PAPVASATETFLRFLSLPKSSAAIVDLRRAAVVIISHLDRMVQPLMPRCLLRG 519
Human 412 --CSSPTSHKGSLQEV--IGW-------------GLIGWKYYANVIGPIQCEGLANLGVTQIACA 459
.::.:|.....|.: :|| ..:.|...:..:..:.| ...:.|:||.
Fly 520 GQATAASSSSAPQQRIYALGWPSLSKDQQGFSAEPTLSWSGESAGVPTLSC----RFQIKQVACC 580
Human 460 EKRFLILSRNGRVYTQAYNSDTLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDG 524
|.:.||||:.|::||.........|..::.:|....:.||.|.:|.|:||:.:....||||.|:.
Fly 581 ETQMLILSQEGKLYTWRLAKPEAEPLPMEEVAHDVFISIAGHCEGRHFLAIDSNHNAYSWGTGED 645
Human 525 GRLGHGDTVPLEEPKVISAFSGKQAGKHVVH-IACGSTYSAAITAEGELYTWGRGNYGRLGHGSS 588
.|||||||.....|..|:|.. :|.|. :.||.:||||||..|.|.|||||.|.|||||:|
Fly 646 HRLGHGDTHARAVPTKIAALE-----QHCVQSVYCGCSYSAAITCGGNLLTWGRGTYARLGHGNS 705
Human 589 EDEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIEK 653
:|.::|.||..|....|:|||.|||||.:||:|..|.|::||||||||||.|..:|...|.|:|.
Fly 706 DDRSLPTLVVALSDHMVVDVALGSGDAHSLALTSEGLVFAWGDGDYGKLGNGNCNGSLQPILVES 770
Human 654 LQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEH----VRYPKLLEGLQGKKVIDV 714
|. .|.:|..|||||:||:.:||:|:|||. ..|||...|. ...|:|:..||.|:::||
Fly 771 LP--RVQRVFAGSQFSVALSSEGQLYTWGKA--TCLGHQLVERSVQGCSVPRLVSSLQHKRIVDV 831
Human 715 AAGSTHCLALTEDSEVHSWGSNDQCQHFDTLRVTKP--EPAALPGLDTKHIVGIACGPAQSFAWS 777
|....|||||:...||..||.||..|.......::| ....|..|.|....||||..|||..|:
Fly 832 AVSVAHCLALSSSGEVFGWGRNDSQQICPASVSSEPLLRTPILVSLPTFPASGIACTSAQSLVWT 896
Human 778 SCSEWSIGLRVPFVVDICSMTFEQLDLLLRQVSEGMDGSAD--WPPPQEKECVAVATLNLLRLQL 840
..|...:..|.|||||:...||..||.|| ||..|.| ..|.||.||:|||.|||.||||
Fly 897 QSSHQGVPRRAPFVVDLGEPTFRLLDQLL-----GMCSSQDNRQTPNQESECIAVACLNLFRLQL 956
Human 841 HAAISHQVDPEFLGLGLGSILLNSLKQTVVTLASSAGVLSTVQSAAQAVLQSGWSVLLPTAEERA 905
.|.|::.|:|..:||..||.||.|||..::.||..:.||.|:|.|||..||.|||||||||.|||
Fly 957 LALIANGVEPRQVGLASGSRLLCSLKTRILGLAGGSQVLRTIQVAAQQALQDGWSVLLPTAAERA 1021
Human 906 RALSALLPCAVSGNEVNISPGRRFMIDLLVGSLMADGGLESALHAAITAEIQDIEAKKEAQKEKE 970
:.|::||| |......|.|.|||.||||.||||:|||||||..||..|
Fly 1022 QTLTSLLP---SEPGQASSAGHRFMTDLLVSSLMAEGGLESALQHAIRLE--------------- 1068
Human 971 IDEQEANASTFHRSRTPLDKDLINTGICESSGKQC-----LPLVQLIQQLLRNIASQTVARLKDV 1030
..|....| |||:|||.:||.|.|:.:..||...
Fly 1069 ---------------------------SSSCSADCGDGVHLPLLQLITRLLSNNAALSQTRLSPT 1106
Human 1031 ARRISSCLDFEQHSRER-------SASLDLLLRFQRLLISKLYPGESIGQTSDISSPELMGVGSL 1088
:....:.|:..||: |.||.||.||||||:|.::..:...:|: |..:|
Fly 1107 ---LGKQQEKEEEEREQQHQEPSTSPSLSLLHRFQRLLLSHIHQAQPEEETT--------GAEAL 1160
Human 1089 LKKYTALLCTHIGDILPVAASIASTSWRH-----------------FAEVAYIVEGDFTGVLLPE 1136
|.:|...| :.|.:|:....| ...:..:::.|.:..||.|
Fly 1161 LLQYMHAL---------IPACVATLQKAHELALQCREPGENSFGQMVGHLGRVLQADISDALLNE 1216
Human 1137 LVVSIVLLLSKNAGLMQEAGAVPLLGG---------LLEHLDRFNHLAPGKERDDHEELAWPGIM 1192
|:|.::|| :......||| ||..|||.|......|..|.:::.||||:
Fly 1217 LLVGLLLL---------KRDRPQCLGGLRWARLFLPLLRVLDRLNRALGEGELRDGDDMGWPGII 1272
Human 1193 ESFFTGQNCRN---------NEEVTLIRKADLENHNKDGGFWTVIDGKVYDIKDFQTQSLTGNSI 1248
||. :.|...:|:||:||...||....::.|.|.|:..:..:|.|..|:
Fly 1273 --------CRGGPKGGPPPADPETHYVRRADMENLLLDGSRCIILAGYVCDLSGYNCESETLRSV 1329
Human 1249 LAQFAGEDPVVALEAALQFEDTRESMHAFC----VGQYL--EPDQEIVTIPDLGSLSSPLIDTER 1307
|....|:| |.|.:..:..|.:|.... :|:|: ...:|..:.|....|:. ..:|.
Fly 1330 LDSGLGKD----LTAEMSSQVHRTAMEHILEHHKLGKYMVQASTEEKSSAPGPSRLTH--FSSEC 1388
Human 1308 NLGLLLGLHASYLAMSTPLSPVEIECAKWLQSSIFSGGLQTSQIHYSYNEEKDE---DH-C-SSP 1367
.|..||||.|:.:.....|.|.|::|.:..:||:.|||||..|....::|||.| .| | |:.
Fly 1389 ALAQLLGLVANLMCSGPALQPAELQCRQLDKSSLLSGGLQLLQPSNPFDEEKGEARSSHSCHSTA 1453
Human 1368 GGTPAS-------KSRLCSHR--RALGDHSQAFLQAIADNNIQDHNVKDFLCQIERYCRQCHLTT 1423
|.||.. :.:|...| ..|...:.||:..:|:..:.:..|..:|...||||:..:|..
Fly 1454 GNTPTELPPPLPMQQQLAPGRGKSQLQLRADAFISGLAEARVSEPPVAAWLALTERYCKAHNLMW 1518
Human 1424 PIMFPPEHPVEEVGRLLLCCLLKHEDLGHVALSLVHAGALGIEQVKHRTLPKSVVDVCRVVYQAK 1488
...|..||||:|:.|||...|::|:.||.:.|: ||..|... |:.:.::.|:|:|||
Fly 1519 HQEFATEHPVQELERLLSAVLIRHQYLGGLVLN-----ALETEVPP----PRQLGEIIRLVHQAK 1574
Human 1489 CSLIKTHQEQGRSYKEVCAPVIERLRFLFNELRPAVCNDLSIMSKFKLLSSLPRWRRIAQKIIRE 1553
.|:::|.|:..|||||||||::||||||..|:|||:......:.:..:|...||::.:.:::::|
Fly 1575 WSVVRTRQQLNRSYKEVCAPILERLRFLLYEVRPAISPQQRGLRRLPILQRPPRFKMLVRRLLQE 1639
Human 1554 RRKKRVPKKPESTDDEEKIGNEESDLEEACILPHSPINVDKRPIAIKSPKDKWQPLLSTVTGVHK 1618
.|..|.|.||| ||..|.|.... :|:|.:: ||.:.:......|.:.:
Fly 1640 LRSSRQPAKPE-------------DLLNASIQQEQ----EKKPQSM--PKQELEEQEEEETLLRR 1685
Human 1619 YKWLKQNVQGLYPQSP-LLSTIAEFALKEEPVDVEKMRKCLLKQLERAEVRLEGIDTILKLASKN 1682
.. ::.:.|.....| |:..|.:||| ::..|||..|:.:..|::|.::||.|:..:.:|...:
Fly 1686 LN--ERQIHGEGELDPALMQDIVDFAL-QDSCDVETARRAMYCQMQRYQLRLAGLQIVQQLLELH 1747
Human 1683 FLLPSVQYAMFCGWQRLIPEGIDIGEPLT------DCLKDVDLIPPFNRMLLEVTFGKLYAWAVQ 1741
.||.:.||::..|:..|..:....|...| ..|..:::|..:.:..|.:...::..|||:
Fly 1748 GLLDAAQYSLLNGFLGLHLKSTSSGGGSTGSGSSLHVLGQLNMISAYQKARLLLAQSRVLDWAVR 1812
Human 1742 NIRNVL---MDASAKFKELGIQPVPLQTITNENPSGPSLGT------IPQARFLLVMLSMLTLQH 1797
.:|.:: ....|:.|: ..:||| :|:|||||.:..:|..:.
Fly 1813 ELRRLVNQEQQGHARGKD-----------------STNLGTYVLLKRLPRARFLLSVFGLLAKEL 1860
Human 1798 GANNLDLLLNSGMLALTQTALRLIGPSCDNVEEDMNASAQGASATVLEET--RKETAPVQLPVSG 1860
|.|.|..|:|||:|. |.|.|:..: ..|........|..:.:.|:: :::::..|| ||
Fly 1861 GPNELGFLINSGLLG---TVLGLLAQT--GGEGATGGQVHGELSILYEDSVLKQKSSKAQL--SG 1918
Human 1861 PELAAMMKIGTRVMRGVDWKWGDQDGPPPGLGRVIGELGEDGWIRVQWDTGSTNSYRMGKEGKYD 1925
|:||.:||||||::||.|||||||||.|||.||:|.|:|||||:||:|.||:||||||||||:||
Fly 1919 PDLAKLMKIGTRIVRGADWKWGDQDGNPPGEGRIISEVGEDGWVRVEWYTGATNSYRMGKEGQYD 1983
Human 1926 LKLAELPA-AAQPSAEDSDTEDDSEAEQTERNIHPTAMMFTSTINLLQTLCLSAGVHAEIMQSEA 1989
|:||:... .|.|:..:.:....|||..|. :.||:.::......|||.|.:..|:|...:..:|
Fly 1984 LQLADSALNVASPTEPEREDVSGSEASPTS-DSHPSKLLRHCAAKLLQILAVGTGLHGAQLDKDA 2047
Human 1990 TKTLCGLLRMLVESGTTDKTSSPNRLVYREQHRSWCTLGFVRSIA-LTPQVCGALSSPQWITLLM 2053
.:.:..:.|.:: ..|.|..| :.|. ..|..|||:|:|: ..|::|..||:|.|::..:
Fly 2048 LRGMTSMFRTII----YPKPSMSN-ISYA---LGWLNLGFIRAISGDCPRLCLELSTPGWLSHYL 2104
Human 2054 KVVEGHAPFTATSLQRQILAVHLLQAVLPSWDKTERARDMKCLVEKLFDFLGSLLTTCSSDVPLL 2118
.::|..|...| .:.||:..:.|||.:|..|...|..| |..||.:||..||.:...|..|..||
Fly 2105 SLLEQPAGNEA-GVYRQLHCLRLLQLILAQWGAEEEPR-MPALVHQLFATLGRIALHCPGDASLL 2167
Human 2119 RESTLRRRRVRPQASLTATHSSTLAEEVVALLRTLHSLTQWNGLINKYINSQLRSITHSFVGRPS 2183
..:..:.| ..|||:||.::|||:|||||.||:|..||.:||.::..:| .:....:...|
Fly 2168 PTAEGKAR-----VLLTASHSGSVAEELVALLRRLHTLPSWNPVINSFLAQKL-CVAAELLAEQS 2226
Human 2184 EGAQLEDYFPDSENPEVGGLMAVLAVIGGIDGRLRLGGQVMHDEFGEGT---VTRITPKGKITVQ 2245
....| |||...| :.||..:||.|.|.|:|....| ||: :...||||:
Fly 2227 HSTAL-----DSEQVFV---LGVLGAMGGHDLRPRVGLHCFH----EGSHMVIASFTPKGR---- 2275
Human 2246 FSDMRTCRVCP------LNQLK-PLPAV-------AFNVNNLPFTEPMLSVWAQLVNLAGSKLEK 2296
|.:.| :..:| .|||| .|:::.||..|.:|:.|..| |.|...|.
Fly 2276 ------CLLAPGGVGSGVGFVKVQLPAVMPHLDHTVFSLSRLPMNEMLLNAWTVL--LYGPAPEL 2332
Human 2297 HKIKKSTKQAFAGQVDLDLLRCQQLKLYILKAGRALLSHQDKLRQILSQPAVQETGTVHTDDGAV 2361
.::..|.. |::||.|||.|||::.:|.....|..||..||:||.|.| .|:::....
Fly 2333 RELPSSAD----GRLDLALLRAQQLQMAVLHTNGVLYRHQVALRRILKQRA---PGSIYASPD-- 2388
Human 2362 VSPDLGDMSPEGP------------QPPMILLQQLLASATQPSPVKAIFDKQELEAAALAVCQCL 2414
.||..|...:.| |.|.:|:|.:|..|||.|||||.:...:|..|||...|.|
Fly 2389 -EPDRSDAESQQPGEQDQQLSSGSGQEPQLLIQCILLRATQASPVKACYSYMDLATAALNCIQSL 2452
Human 2415 AVESTHPSSPGF----EDCSSSEATTPVAVQHIRPARVKRRKQSPV---------PA----LPIV 2462
|.::....|.|. ...:.|....|..|..:....|.|::|.|. || ..::
Fly 2453 ATQAHQELSEGGGVPPNGRALSSPPQPTMVHGVPVYNVARKEQKPSEQVEQKSKWPAAATDAQLI 2517
Human 2463 VQLMEMGFSRRNIEFALKSLTGASGNASSLPGVEALVGWLLDHSDIQVTELSDADTV---SDEYS 2524
.|:|||||:||.:|.|||.| |..|..:|..|.:|.|:|:|.|:....:.: ||: |...|
Fly 2518 GQIMEMGFTRRTVELALKQL---SLQAEIMPTPEQIVQWILEHPDVCANTIEE-DTLPLASSASS 2578
Human 2525 DEEVVEDVDDAAYSMSTGAVVTESQT----------------YKKRADFLSNDDYAVYVRENIQV 2573
.:...:..::...|.||.:..|.|.| ::.|.||.:.|.||:|||..::.
Fly 2579 HDPEADSDNECPSSNSTTSSSTSSDTVEGQPMAVSGPAPPVKFESRKDFQTADLYALYVRGLVRP 2643
Human 2574 GMMVRCCRAYEEVCEGDVGKVIKLDRDGLHDLNVQCDWQQKGGTYWVRYIHVELI--------GY 2630
||.|||||.:||:.:||:|.|:.:|.:||||||||.||:..|.||||.::|:||: ..
Fly 2644 GMTVRCCRDFEEIKQGDMGTVLIVDTEGLHDLNVQVDWRNHGSTYWVCFVHIELVEAAQTHHQPR 2708
Human 2631 PPPSSSSHIKIGDKVRVKAS-----VTTPKYKWGSVTHQSVGVVKAFSANGKDIIVDFPQQSHWT 2690
||| |.:|.:||::.| :..|.....|....::|||. |...|.:.||||.|..|.
Fly 2709 PPP-----IAVGARVRLRTSSLRYGMLCPLRLGRSQGSSAIGVVS--SVRSKQLTVDFPDQPAWQ 2766
Human 2691 GLLSEMELVPSIHPGVTC----DGCQMFPINGSRFKCRNCDDFDFCETCFKTKKHNTRHTFGRIN 2751
|.::|:|||.|.....|. |.|...|
Fly 2767 GHINEVELVASQPTSATLPSLGDSCSQMP------------------------------------ 2795
Human 2752 EPGQSAVFCGRSGKQLKRCHSSQPGMLLDSWSRMVKSLNVSSSVNQASRLIDGSEPCWQS-SGSQ 2815
|..|::.|||.::||.|||:...|..|::||...||| |...
Fly 2796 -----------------------PSDLIEDWSRCIRSLTVSSNEAAAKHLLNGSNQPWQSCSSGP 2837
Human 2816 GKHWIRLEIFPDVLVHRLKMIVDPADSSYMPSLVVVSGGNSLNNLIELKTININPSDTTVPLLND 2880
.:||||||:...:|||.|.:.|.|.|.|:||||:.:..|:.:::|.|...|.:....:.|.|:..
Fly 2838 CRHWIRLELHDRILVHSLTLKVSPEDHSHMPSLLEIRVGDCVDSLKEYTWIPVPAGASRVLLMQQ 2902
Human 2881 CTEYHRYIEIAIKQCRSSGIDCKIHGLILLGRIRAEEED----LAAVPFLASDNEEEEDEKGNSG 2941
...|:.::|:.:|||:::||.|||||:..:| |.::.| ||...||||:..........:|
Fly 2903 VPTYYPWVEVVVKQCQNNGIQCKIHGIKFVG--RRQQPDLQHILANAQFLASEYSAGVGPGSTAG 2965
Human 2942 SLIRKKAAGL------ESAAT----IRTKVFVWGLNDKDQLGGLKGSKIKVPSFSETLSALNVVQ 2996
||. |:||. :...|.|||||||:|||||||||:|||:||:|:|.|..:.
Fly 2966 -------AGAVSTSHEEAAAAPEQDLPCTVMVWGLNDKEQLGGLKGSKVKVPTFSQTISRLRPIH 3023
Human 2997 VAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATA 3061
:||||||||.|:.:||||||||.||||||||::. .||:|.|:..|..||||||||||||:||.|
Fly 3024 IAGGSKSLFIVSQDGKVYACGEGTNGRLGLGVTH-NVPLPHQLPVLRQYVVKKVAVHSGGKHALA 3087
Human 3062 LTVDGKVFSWGEGDDGKLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLG 3126
||:||||||||||:||||||.:|...|||||:|||:.|:|||:|||||||||::|.|||||||||
Fly 3088 LTLDGKVFSWGEGEDGKLGHGNRTTLDKPRLVEALRAKKIRDVACGSSHSAAISSQGELYTWGLG 3152
Human 3127 EYGRLGHGDNTTQLKPKMVKVLLGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKLGRGGSE 3191
|||||||||||||||||:|..|.|.||:|||||||||||||||::|.||||||||||||||||||
Fly 3153 EYGRLGHGDNTTQLKPKLVTALAGRRVVQVACGSRDAQTLALTEDGAVFSWGDGDFGKLGRGGSE 3217
Human 3192 GCNIPQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWGKGDYFRLGHGSDVHVRKPQVVEGLRG 3256
|.:.|..||||:|.||.|||||||||||||::|.|||||||||:|||||.|.||||||.:.||||
Fly 3218 GSDTPHEIERLSGIGVVQIECGAQFSLALTRAGEVWTWGKGDYYRLGHGGDQHVRKPQPIGGLRG 3282
Human 3257 KKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTTVNRKPTLVQGLEGQKITRVACGSSHS 3321
::::||||||||||||||:|||||||||||||||:|.|.||:||.||.||:...:.|||||||||
Fly 3283 RRVIHVAVGALHCLAVTDAGQVYAWGDNDHGQQGSGNTFVNKKPALVIGLDAVFVNRVACGSSHS 3347
Human 3322 VAWTTVDVATPSVHE-PVLFQTARDPLGASYLGVPSDADSSAASNKISGASNSKP-NRPSLAKIL 3384
:||...:.::..... ||.|.:.|||||.|.||: .:|::.....: .:|| |:.||:: .
Fly 3348 IAWGLPNASSDEEKRGPVPFSSTRDPLGGSSLGI-YEAETMQTLKQ-----EAKPLNQSSLSE-S 3405
Human 3385 LSLDGNLAKQQALSHILTALQIMYARDAVVGALMPAAMI----------------------APVE 3427
|:|:...|:|.||.|:|.|:.|:.||..:|.||...:.: ||::
Fly 3406 LALETPAARQAALGHVLRAMSILQARQLIVAALTSHSKVNFKERGAVGGEEDHLIGGPIMGAPLQ 3470
Human 3428 CPSF----SSAAPSDAS--------------AMASPMNGEECMLAVDIEDRLSPNPWQEKREIVS 3474
.... ...||:||: |:...|:| ..:....||..| :|
Fly 3471 LAETIAQGGGEAPADATDAGLQEHSPEAAVDALTGGMSG-----GANTLPPLSAGP-------LS 3523
Human 3475 SEDAVTPSAVTPSAPSASARPFIPVTD-DLGAASIIAETMTKTKEDVESQNKAAGPEPQALDEFT 3538
:..::|.|.....:.|:||.|....:. ...|.|::|.|||:.:|.:...:...| ||:|.
Fly 3524 AFQSLTGSLSMSGSLSSSALPQHKHSRMSASAMSVMAATMTQQEEMLSHISHCHG-----LDDFG 3583
Human 3539 SLLIADDTRVVVDLLKLSVCSRAGDRG-RDVLSAVLSGMGTAYPQVADMLLELCVTELEDVATDS 3602
.||...:.:.:|:||||:||.|.|... ...::..|..:|...|.||.||||.|:|||||:.|..
Fly 3584 GLLGEPEAKSLVELLKLAVCGRCGPPSTSQTIADTLISLGAGTPAVAAMLLETCITELEDLCTSR 3648
Human 3603 QS-GRLSSQPVVVESSHPYTDDTSTSGTVKIPGAEGLRVEFDRQCSTERRHDPLTVMDGVNRIVS 3666
.. |:| .:||:.||||||.|:.:.:|.|:|||||.||:|||.|||||:|:|||.:|||..|:::
Fly 3649 HCLGKL-PKPVMQESSHPYVDNVNVTGVVRIPGAEMLRLEFDSQCSTEKRNDPLVIMDGTGRVLA 3712
Human 3667 VRSGREWSDWSSELRIPGDELKWKFISDGSVNGWGWRFTVYPIMPAAGPKELLSDRCVLSCPSMD 3731
:|||||::.|:.|:|:.||||:|||.||.|||||||||.|:.|||||...|..|||.|||.|||.
Fly 3713 MRSGREFAHWAPEIRVLGDELRWKFSSDSSVNGWGWRFWVHAIMPAATLGESGSDRAVLSQPSMA 3777
Human 3732 LVTCLLDFRLNLASNRSIVPRLAASLAACAQLSALAASHRMWALQRLRKLLTTEFGQSININRLL 3796
||..|||.|| .....|::.|||::||||:||.||..:.|:|:|::|..:|..|
Fly 3778 LVMSLLDSRL-APRQPSVLLRLASALAACSQLGALTTAQRIWSLRKLHAVLLLE----------- 3830
Human 3797 GENDGETRALSFTGSALAALVKGLPEALQRQFEYEDPIVRGGKQLLHSPFFKVLVALACDLELD- 3860
:|......:|:.|::.|...|.||:|||:|.||||..|:||.:||.|.|||||::||
Fly 3831 -------QAPRPQDPSLSTLLQPLIPELLRQYEYEEPQVRGGIHLMHSDYFKTLAALACDMQLDA 3888
Human 3861 TLPCCA----------------ETHKWAWFRRYCMASRVAVALDKRTPLPRLFLDEVAKKIRELM 3909
.||..: :.||||||:|||:|.|||.:|.:||.|||.|..||.||..|::
Fly 3889 ALPATSSSSSSSAAPGAISSTGDVHKWAWFKRYCIAVRVAQSLIRRTELPRAFCLEVRKKFAEML 3953
Human 3910 ADS----------------------------------------ENMD-------------VLHES 3921
..| |..| :|||.
Fly 3954 PSSSSNSNANPGCQSPGASMLNSTTSLSSSTVSNVSPPPGITGEQPDLHCHAHQLESTSTLLHED 4018
Human 3922 HDIFKREQDEQLVQWMNRRPDDWTLSAGGSGTIYGWGHNHRGQLGGIEGAKVKVPTPCEALATLR 3986
|.:|:...|.||:||:|||||||.||.||:.|||||||||||||||:||:::|.|||||||:.||
Fly 4019 HTLFQAPHDAQLLQWLNRRPDDWALSWGGASTIYGWGHNHRGQLGGLEGSRIKTPTPCEALSLLR 4083
Human 3987 PVQLIGGEQTLFAVTADGKLYATGYGAGGRLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHC 4051
||||.||||:|||||.||||:|||||:|||||:||::|.:.||||.|:||||:||||||||||||
Fly 4084 PVQLAGGEQSLFAVTPDGKLFATGYGSGGRLGVGGSDSWAIPTLLGSLQHVFVKKVAVNSGGKHC 4148
Human 4052 LALSSEGEVYSWGEAEDGKLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWG 4116
|||::|||||:|||.||||||||||...|||:::|.|.|:.|.|:|.|.||||.:||:|.:.|||
Fly 4149 LALTTEGEVYAWGEGEDGKLGHGNRMSYDRPKLVEHLNGMSVADIACGSAHSAAITASGHVLTWG 4213
Human 4117 KGRYGRLGHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKLGRGG 4181
|||||||||.||||||:|||||||.|:|.:|||||||||||||:||||.||||||||||||||||
Fly 4214 KGRYGRLGHGDSEDQLRPKLVEALLGYRAIDIACGSGDAQTLCITDDDNVWSWGDGDYGKLGRGG 4278
Human 4182 SDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLGHGSDDHVRRPRQVQGL 4246
|||||:|.||:||.||||||||||||||||||||||||||||||:|||||||.||||||::|..|
Fly 4279 SDGCKLPYKIESLAGLGVVKVECGSQFSVALTKSGAVYTWGKGDFHRLGHGSVDHVRRPKKVAAL 4343
Human 4247 QGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLGDGTTNAIQRPRLVAALQGKKVNRVACGSA 4311
||||:|:|||||||||.|::.||||||||||||||||||..||||||||||||||.:.:|.||||
Fly 4344 QGKKIISIATGSLHCVACSDSGEVYTWGDNDEGQLGDGTVTAIQRPRLVAALQGKHIVKVTCGSA 4408
Human 4312 HTLAWSTSKPASAGKLPAQVPMEYNHLQEIPIIALRNRLLLLHHLSELFCPCIPMFDLEGSLDET 4376
||||.|||:.:...:.....|:||:.::::...||..||:||||.|||.|||:.|..:.|.|
Fly 4409 HTLALSTSQLSERLRPLPNPPLEYDLVRDLAPEALHARLILLHHFSELVCPCLAMLPISGDL--- 4470
Human 4377 GLGPSVGFDTLRGILISQGKEAAFRKVVQATMVRDRQHGPVVELNRIQVKRSRSK-GGLAGPDGT 4440
|:| .|:.:|:...||||||||:|.|||||:|||||:|||||||||||:: .||||.||.
Fly 4471 ----SLG--ALKDVLVYNIKEAAFRKVIQTTMVRDKQHGPVIELNRIQVKRSRNRCNGLAGIDGM 4529
Human 4441 KSVFGQMCAKMSSFGPDSLLLPHRVWKVKFVGESVDDCGGGYSESIAEICEELQNGLTPLLIVTP 4505
|||||||..|:.....::|.||||||||||||||||||||||||||||:|:|||||..||||.||
Fly 4530 KSVFGQMVQKLPLLTQEALALPHRVWKVKFVGESVDDCGGGYSESIAEMCDELQNGSVPLLINTP 4594
Human 4506 NGRDESGANRDCYLLSPAARAPVHSSMFRFLGVLLGIAIRTGSPLSLNLAEPVWKQLAGMSLTIA 4570
|||.|:||||||:||.|...:.:..:||||||||:|||:|||||||:|||||||:||.|..|...
Fly 4595 NGRGEAGANRDCFLLDPTLSSVLQMNMFRFLGVLMGIAVRTGSPLSINLAEPVWRQLTGEVLRPT 4659
Human 4571 DLSEVDKDFIPGLMYIRDNEATSEEFEAMSLPFTVPSASGQDIQLSSKHTHITLDNRAEYVRLAI 4635
||:|||:|::.||:.||:.:...:.|.|:.|||:..||.|.::.||:::|||:..|||||||||:
Fly 4660 DLTEVDRDYVAGLLCIRNMDDDPKLFTALELPFSTSSARGHEVPLSTRYTHISPRNRAEYVRLAL 4724
Human 4636 NYRLHEFDEQVAAVREGMARVVPVPLLSLFTGYELETMVCGSPDIPLHLLKSVATYKGIEPSASL 4700
.:|||||||||.|||:||::|:||||||||:..||:.||||||||||.||||||||||.:||::|
Fly 4725 GFRLHEFDEQVKAVRDGMSKVIPVPLLSLFSAAELQAMVCGSPDIPLGLLKSVATYKGFDPSSAL 4789
Human 4701 IQWFWEVMESFSNTERSLFLRFVWGRTRLPRTIADFRGRDFVIQVLDKYNPPDHFLPESYTCFFL 4765
:.|||||||.|:|.||||||||||||||||||||||||||||:|||:| ||||||||||||||||
Fly 4790 VTWFWEVMEEFTNQERSLFLRFVWGRTRLPRTIADFRGRDFVLQVLEK-NPPDHFLPESYTCFFL 4853
Human 4766 LKLPRYSCKQVLEEKLKYAIHFCKSIDTDDYARIALTGEPAADDSSDDSDNEDVDSFAS 4824
||:||||||.||.||||||||||||||||:|||:|: |||. :::...||.|::|.||
Fly 4854 LKMPRYSCKAVLLEKLKYAIHFCKSIDTDEYARVAM-GEPT--EATGSEDNSDLESVAS 4909
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