Protein Alignment CCNC and CycH

DIOPT Version :10

• Sequence 1: NP_005181.2
• Gene: CCNC / 892
• HGNCID: 1581
• Length: 283
• Species: Homo sapiens
• Sequence 2: NP_524207.1
• Gene: CycH / 40429
• FlyBaseID: FBgn0022936
• Length: 324
• Species: Drosophila melanogaster
• Alignment Length: 298
• Identity: 78/298 - (26%)
• Similarity: 125/298 - (41%)
• Gaps: 60/298 - (20%)

Human     8 SSHYLQWILDKQDLLKE--RQKDLKFL-SEEEYWKLQIFFTNVIQALGEHLKLRQQ--------- 60
            ||....|....:..|.|  .:::.|:: |.||..:.:....:.:.:..|.|.|:|.
  Fly     5 SSQKRSWTFANEGQLMEFRVEQNSKYIESHEEEAQGRDLNEHFLTSAEERLLLKQYEIYLFDFCR 69

Human    61 ---------VIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVL 116
                     |:.||..||||||...|.....|..:..||||:|.|||||.|..|
  Fly    70 RFEPTMPKCVVGTAFHYFKRFYLNNSPMDYHPKEILATCVFVACKVEEFNVSIN----------- 123

Human   117 KTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQD------MGQEDMLLPL 175
              :|......:.....:.:|..|..|:..::..|.:::|:||:..::.|      |...|.|.|.
  Fly   124 --QFVNNIKGDRNKATDIVLSNELLLIGQLNYYLTIHNPFRPIEGFLIDIKTRSNMQNPDRLRPH 186

Human   176 AWRIVNDTYRTDLCLLYPPFMIALAC-LHVACVVQQK-----------DARQWFAELSVDMEKIL 228
            ....::.||.:|.|||:.|..||||. ||.|...|:.           .||:....|...:.|
  Fly   187 IDSFIDSTYYSDACLLHTPSQIALAAVLHAASREQENLDSYVTDLLFVSAREKLPGLIDAVRK-- 249

Human   229 EIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNS 266
              ||:::|.|:|    .:|:::..|..|:.|.:...|:
  Fly   250 --IRIMVKQYQQ----PDREKVKAIEKKLDKCRNQANN 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNC	NP_005181.2	CYCLIN_CCNC_rpt1	40..146	CDD:410217	31/123 (25%)
		CYCLIN_CCNC_rpt2	154..245	CDD:410218	32/108 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..283		4/15 (27%)
CycH	NP_524207.1	ccl1	2..307	CDD:129660	78/298 (26%)