DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCNC and koko

DIOPT Version :10

Sequence 1:NP_005181.2 Gene:CCNC / 892 HGNCID:1581 Length:283 Species:Homo sapiens
Sequence 2:NP_732338.1 Gene:koko / 14462485 FlyBaseID:FBgn0264816 Length:259 Species:Drosophila melanogaster


Alignment Length:209 Identity:46/209 - (22%)
Similarity:84/209 - (40%) Gaps:28/209 - (13%)


- Green bases have known domain annotations that are detailed below.


Human    55 LKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVL-KT 118
            ||::....|.|.:.|.||:........|..|:|...::||.|::|...|....:|..|...| :.
  Fly    47 LKMKPLTAACAAIVFHRFFREVKASDYDEFLIAAGSLYLAGKIKEDESVKIRDVINVAYCTLNRG 111

Human   119 RFSYAFPKEFPYRMNHILECEFYLLELM--DCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIV- 180
            ........|:....:.|::.|..:...:  |..:.:.|.|  ||.|::.:  :|.:....|..| 
  Fly   112 NDPVDLNDEYWSMRDAIVQAELLITRTLCFDLNIDLAHKY--LLHYMKTL--QDWVGTEVWNSVP 172

Human   181 ---------NDTYRTDLCLLYPPFMIALACLHVACVV---------QQKDARQWFAELSVDM--E 225
                     .|.:.:...|.|.|..:|:.||.:|...         :..::..|:..|..|.  |
  Fly   173 IAKAAASYLQDFHHSANILKYKPTHVAIGCLSLALQTYGIQVPLTDESDESAMWYKPLVKDFTRE 237

Human   226 KILEIIRVILKLYE 239
            ...|||..::::|:
  Fly   238 NQWEIIENVIEVYK 251

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCNCNP_005181.2 CYCLIN_CCNC_rpt1 40..146 CDD:410217 21/91 (23%)
CYCLIN_CCNC_rpt2 154..245 CDD:410218 24/107 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 252..283
kokoNP_732338.1 CYCLIN_CCNM_CCNQ_rpt1 32..142 CDD:410237 21/94 (22%)
CYCLIN_CCNM_CCNQ_rpt2 147..252 CDD:410238 24/109 (22%)
Blue background indicates that the domain is not in the aligned region.

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