| Sequence 1: | NP_055421.1 | Gene: | HERC3 / 8916 | HGNCID: | 4876 | Length: | 1050 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001261249.1 | Gene: | Herc4 / 38151 | FlyBaseID: | FBgn0035207 | Length: | 1062 | Species: | Drosophila melanogaster |
| Alignment Length: | 1078 | Identity: | 477/1078 - (44%) |
|---|---|---|---|
| Similarity: | 668/1078 - (61%) | Gaps: | 52/1078 - (4%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQ 65
Human 66 LGHEREGNKPEQ-----IGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSV 125
Human 126 AVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS----PQRVRS 186
Human 187 LEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGE 251
Human 252 EHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLI 316
Human 317 YAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYH-IVKQIFSGGDQTFVLCSK 380
Human 381 YENYSPAVDFRTMN-QAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKK 444
Human 445 IDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLI 509
Human 510 LPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVLYLL--- 571
Human 572 ---------RGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKH--VEYDTFYIPEISNLVDIQE 625
Human 626 DYLMWFLHQAGMKARPSIIQDTV---TLCSYPFIFDAQAKTKMLQTDAELQMQVAV-NGANLQNV 686
Human 687 FMLLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFF 751
Human 752 LLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKK 816
Human 817 LLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTV 881
Human 882 CKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELE 946
Human 947 ETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEY 1011
Human 1012 LPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSL 1049 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HERC3 | NP_055421.1 | RCC1 1 | 1..51 | 17/49 (35%) | |
| ATS1 | 2..331 | CDD:227511 | 162/337 (48%) | ||
| RCC1 2 | 52..101 | 23/53 (43%) | |||
| RCC1 3 | 102..154 | 22/51 (43%) | |||
| RCC1 4 | 156..207 | 23/54 (43%) | |||
| RCC1 5 | 208..259 | 28/50 (56%) | |||
| RCC1 6 | 261..311 | 31/49 (63%) | |||
| RCC1 | 313..377 | CDD:366085 | 26/64 (41%) | ||
| RCC1 7 | 313..366 | 18/53 (34%) | |||
| HECTc | 702..1048 | CDD:238033 | 189/345 (55%) | ||
| Herc4 | NP_001261249.1 | RCC1 | 6..55 | CDD:278826 | 15/47 (32%) |
| RCC1 | 59..110 | CDD:278826 | 21/50 (42%) | ||
| RCC1 | 114..163 | CDD:278826 | 20/48 (42%) | ||
| RCC1 | 167..218 | CDD:278826 | 23/52 (44%) | ||
| RCC1 | 221..270 | CDD:278826 | 27/48 (56%) | ||
| RCC1 | 273..322 | CDD:278826 | 30/48 (63%) | ||
| RCC1_2 | 309..339 | CDD:290274 | 18/29 (62%) | ||
| RCC1 | 327..390 | CDD:278826 | 26/62 (42%) | ||
| HECTc | 715..1060 | CDD:238033 | 189/345 (55%) | ||
| HECTc | 739..1059 | CDD:214523 | 175/320 (55%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 353 | 1.000 | Domainoid score | I1009 |
| eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 909 | 1.000 | Inparanoid score | I368 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG57432 | |
| OrthoDB | 1 | 1.010 | - | - | D1062377at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001110 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41232 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | LDO | PTHR45622 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R774 |
| SonicParanoid | 1 | 1.000 | - | - | X678 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.970 | |||||