Protein Alignment ENDOU and EndoU

DIOPT Version :10

• Sequence 1: NP_001165910.1
• Gene: ENDOU / 8909
• HGNCID: 14369
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_650508.1
• Gene: EndoU / 41931
• FlyBaseID: FBgn0038381
• Length: 322
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 99/329 - (30%)
• Similarity: 154/329 - (46%)
• Gaps: 48/329 - (14%)

Human   107 NARCQEFGNCCKDFE--------SLCSDH--EVSHSSD-AITKEEIQSISEKIYRADTNKAQKED 160
            :|:||:.    |.|.        .:.|.|  |..||.. ..|.:::.::|:.:|..:|..:.
  Fly    16 SAKCQKL----KRFVIVGLLITIGILSWHFYEYFHSKPLPKTPDDVLTLSKNLYAEETEVSP--- 73

Human   161 IVLNSQNCISPSETRNQVDRCPKPLFTYVNEKLFSK---PTYAAFINLLNNYQRATGHGEHFSAQ 222
             .|...|....:.:....||.|:.||. :::.|.::   .|.|..:.|.:||:......||.:.:
  Fly    74 -YLYKVNLQGKTTSGAHDDRAPRNLFE-LHQDLLARDANSTTALLMRLFDNYELDVAVQEHPTPE 136

Human   223 ELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQEFVDD----LKNMWFGLYSRGNEEGDSSGF 283
            .:.||..|||.:|.|.|||....||.|::....|   .||    |:.:||..||||.....||.|
  Fly   137 HVQEQYDFLRAVMGTRVMKLTMRFLVHKDIVSVE---YDDQLRLLQELWFTPYSRGRGIVGSSSF 198

Human   284 EHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIYDGPWDSYPD-------VLAMQFNWDGY 341
            ||||..|::..||.|.|||:.|..:|:.|.|||..      |.::.:       ||::::.:...
  Fly   199 EHVFMAEIRDQKVLGLHNWLYFADQEQRGNVDYKG------WLNHKEMGKHNQMVLSVRYTFHNI 257

Human   342 YKEVGSAFIGSSPEFEFALYSLCFIA-RPGKVCQLSLGGYPLAVRTYTWDKSTYGNGKKYIATAY 405
            .|.|...|:|.|||.:.|||:.||:| ...:.|.:.||.....:.::.|.    .||.:.|.|.|
  Fly   258 NKPVNGFFVGISPELDMALYTACFLATAKEEPCHIQLGHASATIVSHEWK----WNGMRLIGTVY 318

Human   406 IVSS 409
            ..||
  Fly   319 PDSS 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ENDOU	NP_001165910.1	Somatomedin_B	22..61	CDD:460034
		SO	86..128	CDD:197571	7/30 (23%)
		XendoU	140..405	CDD:462792	85/279 (30%)
EndoU	NP_650508.1	XendoU	56..319	CDD:462792	85/280 (30%)