Protein Alignment ENDOU and CG2145

DIOPT Version :10

• Sequence 1: NP_001165910.1
• Gene: ENDOU / 8909
• HGNCID: 14369
• Length: 410
• Species: Homo sapiens
• Sequence 2: NP_572668.1
• Gene: CG2145 / 32027
• FlyBaseID: FBgn0030251
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 101/279 - (36%)
• Similarity: 148/279 - (53%)
• Gaps: 14/279 - (5%)

Human   130 SHSSDAITKEEIQSISEKIYRADTNKAQKEDIVLNSQNCISPSETR--NQVDRCPKPLFTYVNEK 192
            |..:...|.:||:.::|.:|..::| :|..:|.:|.|     ..||  :..|..|.||.| |:.|
  Fly   322 SSGNSVATDDEIRQLTELLYTKESN-SQIGNIQVNLQ-----GRTRSIDSADEAPNPLLT-VDSK 379

Human   193 LFSKPTYAAFINLLNNYQRATGHGEHFSAQELAEQDAFLREIMKTAVMKELYSFLHHQNRYGSEQ 257
            ....||......|.|||:..|...||.:..|..|::.||..:|.|.||::...||..:.....:.
  Fly   380 ALESPTIVKMRLLFNNYEHDTHVNEHVTPNERKEENDFLDAVMATPVMRQAMLFLQQKGVVSPDP 444

Human   258 EFVDDL-KNMWFGLYSRGNEEGDSSGFEHVFSGEVKKGKVTGFHNWIRFYLEEKEGLVDYYSHIY 321
            :...|| |.:||..||||..:..||||||||..|||.|.:.|||||:....|||:|..||..::.
  Fly   445 KTHRDLVKELWFTQYSRGQGKIGSSGFEHVFVYEVKDGTIIGFHNWVYIGDEEKDGRFDYKGYMK 509

Human   322 DGPWDSYPDVLAMQFNWDGYYKEVGSAFIGSSPEFEFALYSLCFIARPGKVCQLSLGGYPLAVRT 386
            :....:...::.::|:..|..|.|.:.|:|:|||.|.|||::||..||.:.|.:|||.....:.|
  Fly   510 EQDIGTKGKIVKIRFSHQGLNKPVNTVFVGTSPELELALYTVCFQLRPDRTCPVSLGNSKFGIVT 574

Human   387 YTWDKSTYGNGKKYIATAY 405
            |:|   .| .||..|.:||
  Fly   575 YSW---RY-RGKNLIGSAY 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ENDOU	NP_001165910.1	Somatomedin_B	22..61	CDD:460034
		SO	86..128	CDD:197571
		XendoU	140..405	CDD:462792	97/267 (36%)
CG2145	NP_572668.1	PHA03247	<47..301	CDD:223021
		XendoU	329..590	CDD:394910	100/272 (37%)