Protein Alignment MTMR2 and Mtmr2

DIOPT Version :10

• Sequence 1: NP_057240.3
• Gene: MTMR2 / 8898
• HGNCID: 7450
• Length: 643
• Species: Homo sapiens
• Sequence 2: XP_036011299.1
• Gene: Mtmr2 / 77116
• MGIID: 1924366
• Length: 718
• Species: Mus musculus
• Alignment Length: 650
• Identity: 626/650 - (96%)
• Similarity: 635/650 - (97%)
• Gaps: 7/650 - (1%)

Human     1 MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLR 65
            |||||||||||:|..|||.||.|||||||||||||||||||||.:||||||||||||||||||||
Mouse    69 MEKSSSCESLGAQLPAARLPSEDSLSSASTSHSENSVHTKSASAISSDSISTSADNFSPDLRVLR 133

Human    66 ESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLG 130
            |:|||||||||.|||||||||||||||||||||||||||||||:|||||||||||||||||||||
Mouse   134 EANKLAEMEEPALLPGENIKDMAKDVTYICPFTGAVRGTLTVTSYRLYFKSMERDPPFVLDASLG 198

Human   131 VINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAF 195
            ||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||
Mouse   199 VISRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNGLPLFAF 263

Human   196 EYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVAS 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   264 EYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVAS 328

Human   261 FRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSV 325
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||
Mouse   329 FRSRGRIPVLSWIHPESQATVTRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSV 393

Human   326 NAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLE 390
            |||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||||
Mouse   394 NAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPTIEETHWLSNLESTHWLE 458

Human   391 HIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLS 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   459 HIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLS 523

Human   456 FGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR-------QFPTAFEFNEYFLITILDHLY 513
            |||||||||||||||||||||||||||||||||||||       |||||||||||||||||||||
Mouse   524 FGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFVVLNLQFPTAFEFNEYFLITILDHLY 588

Human   514 SCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVG 578
            ||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||
Mouse   589 SCLFGTFLCNSEQQRGKENLPKKTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVG 653

Human   579 YYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQTVV 643
            ||||||||||||||||:|||||||||||||:||||||||||||||||||||||||||||||||||
Mouse   654 YYIRWNPRMKPQEPIHSRYKELLAKRAELQRKVEELQREISNRSTSSSERASSPAQCVTPVQTVV 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTMR2	NP_057240.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		47/54 (87%)
		PH-like	73..187	CDD:473070	110/113 (97%)
		Myotub-related	202..528	CDD:461958	323/332 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	615..643		27/27 (100%)
Mtmr2	XP_036011299.1	PH-like	141..255	CDD:473070	110/113 (97%)
		Myotub-related	270..603	CDD:461958	323/332 (97%)