Protein Alignment MTMR2 and mtmr2

DIOPT Version :10

• Sequence 1: NP_057240.3
• Gene: MTMR2 / 8898
• HGNCID: 7450
• Length: 643
• Species: Homo sapiens
• Sequence 2: NP_571446.1
• Gene: mtmr2 / 30644
• ZFINID: ZDB-GENE-990715-14
• Length: 620
• Species: Danio rerio
• Alignment Length: 645
• Identity: 463/645 - (71%)
• Similarity: 540/645 - (83%)
• Gaps: 27/645 - (4%)

Human     1 MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLR 65
            ||:|:|.:            ||:||.|::|:.|:.|    |...:|...:.:..       |.:.
Zfish     1 MEESASVD------------SVESLCSSTTTRSDRS----SGPKLSDTELRSKG-------RPIE 42

Human    66 ESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLG 130
            :..|.....|.||||.|.:::.||||||||||.|.:||:||||||||:|:..:|:|.|.||..||
Zfish    43 KMYKDPSKGELPLLPVELVQESAKDVTYICPFIGPIRGSLTVTNYRLFFRCTDREPVFGLDLPLG 107

Human   131 VINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHK-PEGRTRRSIFENLMKYAFPVSNNLPLFA 194
            |::||||||.|:.||:.||||  .|||:|||||.|| |:...::|:||.|||:|||||||:.|||
Zfish   108 VLSRVEKIGAATGRGDVSYGL--ACKDMRNLRFVHKEPDDSLKKSVFEVLMKFAFPVSNNMSLFA 170

Human   195 FEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVA 259
            ||||:||||||||:||||.|.:|||:|||||||:|:|:.|||||:|||.||||..|.|:||:||:
Zfish   171 FEYKQVFPENGWKVYDPLAECKRQGLPNESWRISKLNDHYELCDSYPATLVVPVTITDDELRRVS 235

Human   260 SFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPS 324
            |||::|||||||||||||||.:.|.||||||.:|:|.|||||.||||||:||||||:||||||||
Zfish   236 SFRAKGRIPVLSWIHPESQAAVVRSSQPMVGQNGRRCKEDEKLLQAIMDANAQSHKLFIFDARPS 300

Human   325 VNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWL 389
            |||.|||.||||:|||||||||||||||||||||||||||||||:|||||||:||||||||||||
Zfish   301 VNAAANKMKGGGFESEDAYQNAELVFLDIHNIHVMRESLRKLKEVVYPNIEESHWLSNLESTHWL 365

Human   390 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWL 454
            ||||||||||||||||||||||||||||||||||||||||||::|||.:|||||||::|||||||
Zfish   366 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLALIMLDSHYRTIRGFQILVEKEWL 430

Human   455 SFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGT 519
            |||||||.|||||||||.|.||||:||||||||||||||||.|||||||||||||||||||||||
Zfish   431 SFGHRFQQRVGHGDKNHTDVDRSPIFLQFIDCVWQMTRQFPAAFEFNEYFLITILDHLYSCLFGT 495

Human   520 FLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWN 584
            |||||||||.||.:|||||||||::|||||:|.||||..||:|||:|...:|||:|||.||||||
Zfish   496 FLCNSEQQRLKEEIPKRTVSLWSFVNSQLEEFVNPLYVHYSSHVLFPTVGIRHLQLWVSYYIRWN 560

Human   585 PRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNR-STSSSERASSPAQCVTPVQTVV 643
            |||:||||:|.||||||||||||||:|||||||:|:| ::||||||.||.:.:|||||.|
Zfish   561 PRMRPQEPVHQRYKELLAKRAELQKRVEELQREVSSRTASSSSERAGSPTRSITPVQTFV 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTMR2	NP_057240.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		14/54 (26%)
		PH-like	73..187	CDD:473070	69/114 (61%)
		Myotub-related	202..528	CDD:461958	279/325 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	615..643		18/28 (64%)
mtmr2	NP_571446.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48		16/69 (23%)
		PH-like	65..161	CDD:473070	61/97 (63%)
		Myotub-related	178..504	CDD:461958	279/325 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	590..620		19/29 (66%)