DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MTMR2 and mtmr2

DIOPT Version :10

Sequence 1:NP_057240.3 Gene:MTMR2 / 8898 HGNCID:7450 Length:643 Species:Homo sapiens
Sequence 2:XP_002935623.3 Gene:mtmr2 / 100494494 XenbaseID:XB-GENE-6044385 Length:570 Species:Xenopus tropicalis


Alignment Length:571 Identity:461/571 - (80%)
Similarity:521/571 - (91%) Gaps:1/571 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    73 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEK 137
            |||..|||||::||:||||||||||:||.||:.|||||||||:|:|||...||||.||:|:|:||
 Frog     1 MEELLLLPGESVKDIAKDVTYICPFSGAYRGSFTVTNYRLYFRSLERDRHLVLDAPLGIISRIEK 65

Human   138 IGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP 202
            ||||:|||||..|:|.||||:||:|||:|.:.|||:|:||||:|:|||::..|||||||||||||
 Frog    66 IGGAASRGENPNGIEIVCKDMRNIRFAYKQDLRTRKSVFENLVKFAFPLNYGLPLFAFEYKEVFP 130

Human   203 ENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRI 267
            |||||:|||:.|||||||||||||||::||||||||||||.|||||||.|:||:::|:||::.||
 Frog   131 ENGWKVYDPIQEYRRQGIPNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQDRI 195

Human   268 PVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKA 332
            ||||||||||||.|||||||:.||:||||||||||||:|||:||||||:||||||||||||||||
 Frog   196 PVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMDANAQSHKVFIFDARPSVNAVANKA 260

Human   333 KGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILA 397
            ||||||||||||||||||||||||||||||.||||||.||:|:|.:|||||||||||||||||||
 Frog   261 KGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKLILA 325

Human   398 GALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQL 462
            |||||||||||||||||||||||||||.|||||||:||||||||||||||||||||:||||||..
 Frog   326 GALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHRFYQ 390

Human   463 RVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQ 527
            |.||||||||||||||:||||||||||||||||.||||||:|||.||||||||||||||||.|.|
 Frog   391 RTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNCELQ 455

Human   528 RGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEP 592
            :.||.:.:.:|||||:||||||||.||||.:||:||||||.|.|:||||.|||||||||.:|...
 Frog   456 KLKEGVVEESVSLWSFINSQLEDFINPLYVNYSSHVLYPVTSTRNLELWAGYYIRWNPRTRPPGA 520

Human   593 IHNRYKELLAKRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQTVV 643
            |::|||.||||||||||::|||||||||||||||:|.||| |.:|.|||||
 Frog   521 INSRYKVLLAKRAELQKRLEELQREISNRSTSSSDRGSSP-QPITSVQTVV 570

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MTMR2NP_057240.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
PH-like 73..187 CDD:473070 80/113 (71%)
Myotub-related 202..528 CDD:461958 285/325 (88%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 615..643 21/27 (78%)
mtmr2XP_002935623.3 PH-like 1..115 CDD:473070 80/113 (71%)
Myotub-related 130..455 CDD:461958 285/324 (88%)
Blue background indicates that the domain is not in the aligned region.

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