Protein Alignment SLC5A6 and DUR3

DIOPT Version :10

• Sequence 1: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Sequence 2: NP_011847.1
• Gene: DUR3 / 856370
• SGDID: S000001008
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 581
• Identity: 120/581 - (20%)
• Similarity: 200/581 - (34%)
• Gaps: 180/581 - (30%)

Human    55 TVGELLMADRKMGCLPVALSLLATFQSAVAILGVPSEIYR---FGTQYWFLGCCYFLGLLIPAHI 116
            |..|...|.|.:....||.::::::.....:|...::.|.   ||...:..|.|:    .|.|..
Yeast    44 TAEEFTTAGRSVKTGLVAAAVVSSWIWCSTLLTSSTKEYADGIFGGYAYAAGACF----QIIAFA 104

Human   117 FIPVFYRLHLTSAYEYLEL---RFNKTVRVCGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWL 178
            .:.:..:....:|:.||||   |:.|....|.....|...::...::|.:.|...:.:||.:...
Yeast   105 ILAIKTKQMAPNAHTYLELVRTRYGKIGHGCYLFYAIATNILVTSMLLTSGSAVFSDLTGMNTIA 169

Human   179 SVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKV-------GGLGRVW---- 232
            |...|.:...|||..||:||...||...|.|:.:    :::|.:.||       |..|:|:
Yeast   170 SCFLLPVGVVVYTLFGGIKATFLTDYMHTCVIII----IVLVFAFKVYATSDVLGSPGKVYDLVR 230

Human   233 AVASQH---GRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYG------VNQAQVQRYLSSRTEK 288
            ..|.:|   |...|         .:...|....|:.::::|.|      ::.....:.:|:  ..
Yeast   231 EAAKRHPVDGNYQG---------EYMTMTSKSAGILLIINLIGNFGTVFLDNGYWNKAISA--SP 284

Human   289 AAVLSCYAV--FPFQQVSLCVGCLIGLVMFAY-----YQEYPMSIQQAQAAPDQFVLYFVMDLLK 346
            ||.|..||:  ..:..|...:...:||...|.     :..||..:...||.             .
Yeast   285 AASLKAYAIGGLAWFAVPSLISLTMGLACLAVETSPNFPTYPDPLTSFQAN-------------S 336

Human   347 GLPGLPGLFIA------------CLFSGSLSTISSAFNSLATVTMEDLIRPWF-PEFSEARAIML 398
            ||. ||...||            .:|....|.:|:...::::|...|:.|.:. |..|..:.|..
Yeast   337 GLV-LPAAAIAIMGKGGAVASLLMIFMAVTSAMSAELIAVSSVFTYDIYREYIDPRASGKKLIYT 400

Human   399 SR------GLA---FGYGLLC--LGMAYISSQMGPVLQAAI------------SIFGMVGGPLLG 440
            |.      |||   |..||..  :.|.||...||.::.:|:            ::...|..|:||
Yeast   401 SHVACIFFGLAMSGFSVGLYYGGISMGYIYEMMGIIISSAVLPVVLTLCSKDMNLVAAVVSPILG 465

Human   441 LFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTSMGSSMPPSPSNGSSFSLPTNLTVATVT 505
                                 .||.:..|:    :.|.               ||...|||.|..
Yeast   466 ---------------------TGLAIMSWL----VCTK---------------SLYKELTVDTTF 490

Human   506 TLMPLTTFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVL 566
            ...|:.|                             |.:|:|         |:||...|:|
Yeast   491 MDYPMLT-----------------------------GNLVAL---------LSPAIFIPIL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	115/563 (20%)
DUR3	NP_011847.1	SLC5sbd_DUR3	14..517	CDD:271370	120/581 (21%)