Protein Alignment SLC5A6 and slc5a6

DIOPT Version :10

• Sequence 1: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Sequence 2: XP_031757499.1
• Gene: slc5a6 / 448188
• XenbaseID: XB-GENE-5737332
• Length: 638
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 417/639 - (65%)
• Similarity: 493/639 - (77%)
• Gaps: 30/639 - (4%)

Human    24 FSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAILGV 88
            |:.:||::||||||||.|||||:|..|..:.|:.|.|:|:|.|..||::||||||||||||||||
 Frog     3 FTTVDYIIFVLLLVLSSAIGLYYALSGGKQRTMQEFLLANRSMSFLPISLSLLATFQSAVAILGV 67

Human    89 PSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVRVCGTVTFIFQM 153
            |||||||||:||||||.|.:||||||||||||||||.|||.||||||||:|.||:||||||||||
 Frog    68 PSEIYRFGTEYWFLGCSYIIGLLIPAHIFIPVFYRLRLTSTYEYLELRFSKAVRICGTVTFIFQM 132

Human   154 VIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQLAVI 218
            |||||||||||:||.||||||.||.:||::|:|||:||.||||||||||||.||||||.||||||
 Frog   133 VIYMGVVLYAPALAFNAVTGFSLWGAVLSMGLVCTLYTTLGGLKAVIWTDVIQTLVMFAGQLAVI 197

Human   219 IVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQRYLS 283
            |||:.||||..:||.:|:::.:|:|...:||||.||:||:||.||:|||||||||||||||||||
 Frog   198 IVGTIKVGGFDQVWNIATENNKIAGVNWNPDPFERHSFWSLAIGGIFMMLSLYGVNQAQVQRYLS 262

Human   284 SRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLLKGL 348
            |||||.|:||||||||.||:.|.:|||.||||||||:..|.:..|..:.|||.|||||||:||.|
 Frog   263 SRTEKEAILSCYAVFPCQQLVLALGCLTGLVMFAYYKINPSAYPQDISVPDQMVLYFVMDILKDL 327

Human   349 PGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEARAIMLSRGLAFGYGLLCLGM 413
            |||||||:||||||:||||||||||||||||:|||:|.||..:|::|..||:|||.|||||||||
 Frog   328 PGLPGLFVACLFSGALSTISSAFNSLATVTMQDLIKPHFPSLTESQATWLSKGLALGYGLLCLGM 392

Human   414 AYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWIGIGSIVTS 478
            |||||.||.|||||:|||||||||||||||||.|||..|..||:.||.|||||||||||||.||.
 Frog   393 AYISSLMGSVLQAALSIFGMVGGPLLGLFCLGFFFPFTNSIGAMSGLAAGLVMAFWIGIGSFVTR 457

Human   479 MGSSMPPSPSNGSSFSLPTNLTVATVTTLMPLTTFSKP-TGLQRFYSLSYLWYSAHNSTTVIVVG 542
            |.|..||...|.:|.....|||...::||:...|..|. :|||:||||||:||||||||||::||
 Frog   458 MPSVPPPPLLNATSVPDFGNLTTTVMSTLLTSPTAKKSVSGLQKFYSLSYMWYSAHNSTTVVIVG 522

Human   543 LIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLHCRSYGQDHL-DTG------------ 594
            ||||||||..:||.::|.|:|.||||||..||...:::|.   ||..|: :.|
 Frog   523 LIVSLLTGPTKGRDIDPRTVYLVLPKLLFFLPERYREKLR---YGVPHIVEVGDCLSPRLLQVPY 584

Human   595 --------LFPEKPRNGVL-GDSR--DKEAM--ALDGTAYQGSSSTCILQETSL 635
                    |..||..||.| |:::  :||.|  .|.|.....:..:.::|||||
 Frog   585 DEHSPPHDLVTEKSCNGFLNGNAKYSEKEEMEEKLSGFTRSDTGHSYVVQETSL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	380/526 (72%)
slc5a6	XP_031757499.1	SLC5-6-like_sbd	3..530	CDD:444915	380/526 (72%)