Protein Alignment SLC5A6 and CG6723

DIOPT Version :9

• Sequence 1: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Sequence 2: NP_650069.2
• Gene: CG6723 / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 602
• Identity: 203/602 - (33%)
• Similarity: 324/602 - (53%)
• Gaps: 74/602 - (12%)

Human    21 MSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGE--LLMADRKMGCLPVALSLLATFQSAV 83
            :..|:..|||.||.:.:|.:.||:|.   |:...:|.|  .::..|||..:|:|.||:|:|.|.:
  Fly    11 LQRFAWPDYVAFVSMFLLCIGIGIYF---GFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGI 72

Human    84 AILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIF-IPVFYRLHLTSAYEYLELRFNKTVRVCGTV 147
            .:||:|:|:|.:|.||.::. |..:|:.:...:| :|||:.|::||.|||||:||::.:|:.|:|
  Fly    73 TLLGLPTEVYSYGIQYLYVS-CGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRFDRRLRLYGSV 136

Human   148 TFIFQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFL 212
            .|....|.|:.:|:|.|:||.|.|||..:......:.|:|..||:|||||||:||||.|.:.| |
  Fly   137 MFAIMNVAYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISM-L 200

Human   213 GQLAVI-IVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQA 276
            |.|.:: |.|:..:||.|.|...|....|:...:|..||.||||||.|.|||:........|:|.
  Fly   201 GALCLVAIKGTRDIGGAGVVLERAWSSDRLEAPDLSIDPTVRHTFWCLFFGGIVYWTQTNAVSQN 265

Human   277 QVQRYLS----SRTEKAAVLSCYAVFPFQQVSLCVGCLI--------GLVMFAYYQEY-PMSIQQ 328
            .:|||||    ....||..:            .|||.||        ||:::|.||.. |::.:.
  Fly   266 MIQRYLSLPSLGDARKALCI------------FCVGVLILMALCGYNGLLIYATYQNCDPLTTKL 318

Human   329 AQAAPDQFVLYFVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEFSEA 393
            |:|. ||.:..|||..|..|||:.|||||.:||.:||::|:..||::.|.:||.::|:..:...:
  Fly   319 AKAR-DQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNSMSAVVLEDFVKPYVKKPLSS 382

Human   394 RAI-MLSRGLAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAV 457
            .|| .:.|.:..|.|:||:.:.|:...||.|||..:|:..:..|||.|:|.:|:|.|..|...|:
  Fly   383 SAINWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAITNGPLFGIFTIGLFLPWINGNSAL 447

Human   458 VGLLAGLVMAFWIGIGS--IVTSMGSSMPPSPSN----GSSFSLPTNLT-----VATVTTLMPLT 511
            ||.:.|::...|:.:.:  .:.|...:....|.|    ..||::.|:|.     .|:...:.||
  Fly   448 VGGVMGVIAMSWVSLNAQWAIASGAITYKTKPLNVEQCDYSFNVTTSLANTTHLGASAEDIFPL- 511

Human   512 TFSKPTGLQRFYSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLS 576
                       |.:||:||:...::..|.|.|:.:.:.|:.....::|..:.|.:.|..
  Fly   512 -----------YRISYMWYTTFGASITIFVALLGTFVFGKNNPNKVDPVLLTPCIRKFF------ 559

Human   577 CQKRLHCRSYGQD-HLD 592
                    ::|.: |:|
  Fly   560 --------AFGSEKHMD 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	196/554 (35%)
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	195/549 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.820