Protein Alignment SLC5A6 and CG10444

DIOPT Version :10

• Sequence 1: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Sequence 2: NP_611465.2
• Gene: CG10444 / 37294
• FlyBaseID: FBgn0034494
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 561
• Identity: 222/561 - (39%)
• Similarity: 326/561 - (58%)
• Gaps: 37/561 - (6%)

Human    21 MSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAI 85
            :.||...|..|.:.:||:|..||:|:...|..:.|..|.||||:.|...||:.||:|:|.||:::
  Fly     3 VGTFDAWDAAVLITILVISALIGIYYRYTGGKQKTTQEYLMADQSMTTFPVSFSLMASFMSAISL 67

Human    86 LGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVRVCGTVTFI 150
            :||.:|.|.|||.:..:...|.|...|.|:.|:|||||:..||.|||||.||.:..|:..::.|.
  Fly    68 MGVSNESYEFGTIFCVINIAYVLSTPIAAYFFLPVFYRMRTTSVYEYLERRFGQATRLSASLAFT 132

Human   151 FQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQL 215
            .|||:|||:.||||:|||.||||....::::.:|:|||.|:.|||||||:.|||||:.:||....
  Fly   133 VQMVLYMGIALYAPALALEAVTGIHRSMAIVVIGLVCTFYSTLGGLKAVLITDVFQSFLMFAAIY 197

Human   216 AVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQR 280
            |||.|.:.|.||...:|.||.:.||::..|...||.||||:|:|..||:...||||||||.||||
  Fly   198 AVIAVSAIKAGGFAAIWDVAVERGRVNFIEFSLDPTVRHTWWSLIIGGMVTYLSLYGVNQTQVQR 262

Human   281 YLSSRTEKAAVLSCYAVFPFQQVSLCVGCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFVMDLL 345
            .||.|..|:|..:.:...|...:........||.:|.||::....::......||.:..|.::.:
  Fly   263 LLSVRNLKSAQSALWWNLPILGMLSFSTIFSGLSIFYYYRDCDPLLKGRIDKRDQIMPLFALETM 327

Human   346 KGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFP-----EFSEARAIMLSRGLAFG 405
            ...|||.|||::.:||.||||||||..||:.||:||.::|.:.     ...::::.|.::.:|..
  Fly   328 GQYPGLCGLFVSGIFSASLSTISSAVTSLSAVTLEDYLKPLYKAIFKRTLIDSKSTMPTKIVACI 392

Human   406 YGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVMAFWI 470
            :||||:|:|:::..||.||||:::|||:||||||.:|.||:....:|..|.::|.|..|:::||:
  Fly   393 FGLLCIGLAFVAGSMGGVLQASLTIFGVVGGPLLAIFTLGVCTTRSNQRGVLLGFLVSLIVSFWM 457

Human   471 GIGSIVTSMGSSMPPSPSNGSSFSLPTNLTVAT-----VTTLM--PLTTFSKPTGLQ------RF 522
            |.|.          |.|.       |..|..:|     .|.:|  .:...||.:|:.      ..
  Fly   458 GFGG----------PKPK-------PVTLEFSTAGCENATAVMARAIELSSKSSGVVIEPDYFWL 505

Human   523 YSLSYLWYSAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIY 563
            |.:||||.|.......:|||...|::.... |::.| |.||
  Fly   506 YRISYLWLSVIGFLIAVVVGYFSSIVLAHC-GKAEN-AEIY 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	216/543 (40%)
CG10444	NP_611465.2	SLC5sbd_NIS-SMVT	9..531	CDD:271383	215/538 (40%)