Protein Alignment SLC5A6 and CG32669

DIOPT Version :10

• Sequence 1: NP_066918.2
• Gene: SLC5A6 / 8884
• HGNCID: 11041
• Length: 635
• Species: Homo sapiens
• Sequence 2: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 572
• Identity: 219/572 - (38%)
• Similarity: 327/572 - (57%)
• Gaps: 42/572 - (7%)

Human    21 MSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVALSLLATFQSAVAI 85
            |:|....||.:..::|::|:|||:|:...|..:.|..|.|:|||.|...|||.||:|:|.|||.|
  Fly     1 MATLGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTI 65

Human    86 LGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYLELRFNKTVRVCGTVTFI 150
            |||..|.|::||.:..:...|.|...:.|::.|||||||...|.||||||||....|:..:::|.
  Fly    66 LGVSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFS 130

Human   151 FQMVIYMGVVLYAPSLALNAVTGFDLWLSVLALGIVCTVYTALGGLKAVIWTDVFQTLVMFLGQL 215
            .|||:|||:|:|||:|||.||||.....|::.:|:|||.|..|||:|||:.||::|:|:||....
  Fly   131 LQMVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVF 195

Human   216 AVIIVGSAKVGGLGRVWAVASQHGRISGFELDPDPFVRHTFWTLAFGGVFMMLSLYGVNQAQVQR 280
            :|||....|.|.|..:|.||.::|||:......||..|||::|...||....|::|||||.||||
  Fly   196 SVIICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQR 260

Human   281 YLSSRTEKAAVLSCYAVFPFQQVSLCV----GCLIGLVMFAYYQEYPMSIQQAQAAPDQFVLYFV 341
            .::.::..||..:.:...|.    ||:    .|..||.::.||::....::....:.||.:..||
  Fly   261 LMAVKSLSAARAALWWCLPI----LCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQVMPLFV 321

Human   342 MDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFP-----EFSEARAIMLSRG 401
            :|.:....||.|||::.:|..|||||||..:|||.||:||.::|...     ..::.:.:..|:.
  Fly   322 VDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTLWYSKL 386

Human   402 LAFGYGLLCLGMAYISSQMGPVLQAAISIFGMVGGPLLGLFCLGMFFPCANPPGAVVGLLAGLVM 466
            |:..:|.||:|||:::..:|.:||||:||||::||||||||.|||:...||..||:.|||..|..
  Fly   387 LSLFFGALCIGMAFMAGSIGGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGLLISLAF 451

Human   467 AFWIGIGSIVTSMGSSMPPSPS-NGSSFSLPTNLTVATVTTLMPLTTFSKPTGLQRFYSLSYLWY 530
            .||||       .|...||..| :.|:...|.:.:.|....|..:...::.......|.:||:||
  Fly   452 CFWIG-------FGQPKPPLVSLDMSTAGCPVDRSFARDIFLKTVIAVAEEEHYFYLYRISYMWY 509

Human   531 SAHNSTTVIVVGLIVSLLTGRMRGRSLNPATIYPVLPKLLSLLPLSCQKRLH 582
            :|        :|.:::...|.:             |..|.:||.....:|::
  Fly   510 AA--------LGFLITFFGGWL-------------LSWLFALLKWDNNRRIY 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A6	NP_066918.2	SLC5sbd_SMVT	24..550	CDD:271394	211/535 (39%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	213/551 (39%)