Protein Alignment FUBP1 and mub

DIOPT Version :10

• Sequence 1: XP_016858228.1
• Gene: FUBP1 / 8880
• HGNCID: 4004
• Length: 688
• Species: Homo sapiens
• Sequence 2: NP_001246875.1
• Gene: mub / 40436
• FlyBaseID: FBgn0262737
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 135/607 - (22%)
• Similarity: 200/607 - (32%)
• Gaps: 185/607 - (30%)

Human   133 VGFIIGRGGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLL--------DQIV 189
            ||.|||:.||.::|.::|||.||.|:  .|..|||...::||..::.||..|:        .|..
  Fly    35 VGSIIGKKGEIVNRFREESGAKINIS--DGSCPERIVTVSGTTNAIFSAFTLITKKFEEWCSQFN 97

Human   190 EKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADK 254
            :.|:.        |.......:::|||:.|.:|||.|..||::::..|..:.:..:...|: .::
  Fly    98 DVGKV--------GKTQIPIRLIVPASQCGSLIGKSGSKIKEIRQTTGCSIQVASEMLPNS-TER 153

Human   255 PLRITGDPYKVQQA-KEMVLELIRD--QGGFREVR------------NEYGSRIGGNEGIDV--- 301
            .:.::|...::.|. .::.|.::..  :|.....|            |.....|.||..:..
  Fly   154 AVTLSGSAEQITQCIYQICLVMLESPPRGATIPYRPKPQVTGPVILANGQAFTIQGNYAVPTQET 218

Human   302 ----PIPRFAVGIVIGRNG---EMIKKIQNDAGVRIQFKPDDGTTPERIAQITGPPDRCQHAAEI 359
                |:.....|:..|.:|   .::|      |..:|     |..|.....:...||..::....
  Fly   219 CPVFPLALATGGLHAGISGLADPLLK------GAHLQ-----GAIPAHHHHLQQMPDVAKNPLAS 272

Human   360 ITDL-LRSVQAGNPGGPGPGGRGRGRGQGNWNMGPPGGLQEFNFIVPTGKTGLIIGKGGETIKSI 423
            :..| |..:...:.||.........|.|          .|:....|.....|.||||||..|..|
  Fly   273 LAALGLAGMNPASTGGINHTANPANRAQ----------QQQHEMTVSNDLIGCIIGKGGTKIAEI 327

Human   424 SQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIG-GPVNPLGPPVPHGPHGVP 487
            .|.|||.|.:............:..||.|.|..:..|:.||...:. ...|.|
  Fly   328 RQISGAMIRISNCEEREGGNTDRTITISGNPDSVALAQYLINMSVELQKANLL------------ 380

Human   488 GPHGPPGPPGPGTPMGPYNPAPYNPGPPGPAPHGPPAPYAPQGWGNAYPHWQQQAPPDPAKAGTD 552
                                               ....:.|..|.|       |.|..|.||..
  Fly   381 -----------------------------------EQAQSQQNGGAA-------AAPGAAAAGVA 403

Human   553 PNSAAWAAYYAHYYQQQAQPPPAAPAGAPTT-TQTNGQG-------------DQQNPAPAG---- 599
            ..:.|.|             |.:|..||.|| |.|:|.|             :..|||..|
  Fly   404 AVTGAAA-------------PTSATNGAITTVTLTSGTGVVGAGAAGAAGVANGANPAANGGGSN 455

Human   600 ----QVDYTKAWEEYYKKMGQAVPAPTGAPPGGQPDYSAAWAEYYRQQAAYYAQTSPQGMPQHPP 660
                ...|..|      ..|||.....|..|                 ||..|.:||..     .
  Fly   456 GTISATGYASA------NGGQATNGSVGVNP-----------------AAAAALSSPLA-----S 492

Human   661 APQCLPRPSTLGSAAKSTSAED 682
            |.|.|.:|..| ||..:.||.|
  Fly   493 ALQLLTKPGAL-SALSNLSALD 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FUBP1	XP_016858228.1	KH-I_FUBP1_rpt1	119..193	CDD:411906	24/67 (36%)
		KH-I_FUBP1_rpt2	207..276	CDD:411909	15/69 (22%)
		KH-I_FUBP1_rpt3	297..364	CDD:411912	12/77 (16%)
		KH-I_FUBP1_rpt4	397..468	CDD:411915	23/70 (33%)
		DUF1897	623..>643	CDD:462653	2/19 (11%)
mub	NP_001246875.1	KH-I_PCBP_rpt1	26..92	CDD:411866	23/58 (40%)
		KH-I_PCBP_rpt2	107..177	CDD:411806	15/70 (21%)
		KH-I_PCBP_rpt3	301..371	CDD:411867	23/69 (33%)