Protein Alignment FUBP1 and Psi

DIOPT Version :10

• Sequence 1: XP_016858228.1
• Gene: FUBP1 / 8880
• HGNCID: 4004
• Length: 688
• Species: Homo sapiens
• Sequence 2: NP_995862.1
• Gene: Psi / 36889
• FlyBaseID: FBgn0014870
• Length: 797
• Species: Drosophila melanogaster
• Alignment Length: 777
• Identity: 243/777 - (31%)
• Similarity: 326/777 - (41%)
• Gaps: 233/777 - (29%)

Human    11 SSGSAGGGGGGGGGGGVNDAFKDALQRARQIAAKIGGDAGTSLNSNDYGYGGQKRPLEDGDGSWT 75
            ||||.||||||||.||.  :...|:.:|..:||::...||||..
  Fly    82 SSGSGGGGGGGGGPGGA--SITQAIAQAAAVAARLAASAGTSCE--------------------- 123

Human    76 SPSSTTHWEGMPSPFKDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYKVPDGMVGFIIGR- 139
                                                            |:.::|:.:.|..:||
  Fly   124 ------------------------------------------------EQIRLPESVAGAFMGRS 140

Human   140 GGEQISRIQQESGCKIQIAPDSGGLPERSCMLTGTPESVQSAKRLLDQIVEK------------G 192
            ..:.|:.||.|||.|:|:..|.    :|..||.|..::|...:.::..:..:            .
  Fly   141 SNDTITHIQAESGVKVQVMQDQ----DRVIMLRGQRDTVTKGREMIQNMANRAGGGQVEVLLTIN 201

Human   193 RPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGADKPLR 257
            .|.|| ..|..|   .||||||.:|.||||||||:|||||||:.|.||::||||| |....||||
  Fly   202 MPPPG-PSGYPP---YQEIMIPGAKVGLVIGKGGDTIKQLQEKTGAKMIIIQDGP-NQELIKPLR 261

Human   258 ITGDPYKVQQAKEMVLELI-------RDQG-------------GFREVRNEYGSRIGGNEGIDVP 302
            |:|:..|::.||:|||:||       :.||             ||....|.     .|.|..:|.
  Fly   262 ISGEAQKIEHAKQMVLDLIAQKDAQGQQQGGRGGGGGGGGPGMGFNNFNNG-----NGGESTEVF 321

Human   303 IPRFAVGIVIGRNGEMIKKIQNDAGVRIQF---KPDDGTTPERIAQITGPPDRCQHAAEIITDLL 364
            :|:.|||:|||:.|:||:|||.:.|.::||   |.|:  ..:|...|.|...:...|...|..|:
  Fly   322 VPKIAVGVVIGKGGDMIRKIQTECGCKLQFIQGKNDE--MGDRRCVIQGTRQQVDDAKRTIDGLI 384

Human   365 RSV-------QAGNPGGPGPGGRGRGRGQGNWNMG-----PPGGLQEFNFIVPTGKTGLIIGKGG 417
            .:|       :.||.||.||||   ..|..|:..|     ..||.:|..|:||..|.|::||:||
  Fly   385 ENVMQRNGMNRNGNGGGGGPGG---DSGNSNYGYGYGVNHAQGGREEITFLVPASKCGIVIGRGG 446

Human   418 ETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEEKIGGPVNPLG-PPVPH 481
            ||||.|:|||||..|:.||  .:..||.|||..:||..|::.|||:|.|||...:|.:. .|:..
  Fly   447 ETIKLINQQSGAHTEMDRN--ASNPPNEKLFKSKGTTDQVEAARQMISEKINMELNVISRKPIGG 509

Human   482 GPHGVPGPHG-----------PPGPPGPGTPMG--PYNPAPYNPGPPGPAPHGPPAPYAPQGWGN 533
            ||.|..|..|           ..|..|.....|  |.:.|.|...|.|       .||..|||.
  Fly   510 GPGGGGGNSGGGQNNSHHNQQQGGYGGQNQMQGGDPNSGAGYQQQPWG-------GPYGQQGWD- 566

Human   534 AYPHWQQQ---------APPDPAKAGTDPNSAAWAAYY--------AHYYQQQAQPPPAAPAGAP 581
              |..|||         :....|..|.| .||.|..||        |...:||.:...|..:..|
  Fly   567 --PSGQQQQMAMANQGGSAAGGASGGQD-YSAQWIEYYKQMGCHREAEMIEQQMKAKQAGGSSGP 628

Human   582 TTTQTNGQGDQQNP----APAGQVDYTKAWEEYYKKMGQ-----------------------AVP 619
            ...|...|..|...    |.||..||:..|.|||:.:|:                       :.|
  Fly   629 VQQQQPQQQQQSQQQTGGAGAGGADYSAQWAEYYRSVGKIEEAEAIEKTLKNKQQNGSGGQSSTP 693

Human   620 APT-GAPPGGQPDYSAAWA------------------EYYRQQAAYYAQTS-----PQGMPQ 657
            .|: |.....||:.:||.|                  ..|.|.:.|||..:     |||.||
  Fly   694 NPSQGGSGQQQPNPAAAAAAAAAAAAAAGGYGQSMTPTQYAQYSQYYAAAAAAGGQPQGAPQ 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FUBP1	XP_016858228.1	KH-I_FUBP1_rpt1	119..193	CDD:411906	19/86 (22%)
		KH-I_FUBP1_rpt2	207..276	CDD:411909	43/68 (63%)
		KH-I_FUBP1_rpt3	297..364	CDD:411912	25/69 (36%)
		KH-I_FUBP1_rpt4	397..468	CDD:411915	36/70 (51%)
		DUF1897	623..>643	CDD:462653	7/37 (19%)
Psi	NP_995862.1	KH_1	123..184	CDD:459630	19/133 (14%)
		KH-I_FUBP_rpt2	214..280	CDD:411825	43/66 (65%)
		KH-I_FUBP_rpt3	317..384	CDD:411826	24/68 (35%)
		KH-I_FUBP_rpt4	428..494	CDD:411827	35/67 (52%)
		DUF1897	591..619	CDD:462653	9/28 (32%)
		DUF1897	<653..680	CDD:462653	7/26 (27%)