| Sequence 1: | NP_003891.1 | Gene: | SQSTM1 / 8878 | HGNCID: | 11280 | Length: | 440 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_507738.1 | Gene: | sqst-3 / 188950 | WormBaseID: | WBGene00012067 | Length: | 229 | Species: | Caenorhabditis elegans |
| Alignment Length: | 131 | Identity: | 28/131 - (21%) |
|---|---|---|---|
| Similarity: | 55/131 - (41%) | Gaps: | 24/131 - (18%) |
- Green bases have known domain annotations that are detailed below.
|
Human 571 DGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAK---------LIILENTIYLFSKEGS 626
Human 627 IEIDIPVPKYL---SSVSSQETQGGPLAPMTGTIEKVF--------VKAG-DK-VKAGDSLMVMI 678
Human 679 A 679 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| SQSTM1 | NP_003891.1 | Interaction with LCK. /evidence=ECO:0000269|PubMed:8650207 | 2..50 | ||
| PB1_p62 | 4..102 | CDD:99723 | |||
| Interaction with PRKCZ and dimerization. /evidence=ECO:0000250|UniProtKB:O08623 | 43..107 | ||||
| Interaction with PAWR. /evidence=ECO:0000269|PubMed:11755531 | 50..80 | ||||
| Interaction with GABRR3. /evidence=ECO:0000250|UniProtKB:O08623 | 122..224 | ||||
| ZZ_NBR1_like | 126..168 | CDD:239080 | |||
| LIM protein-binding (LB) | 170..220 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 196..235 | ||||
| TRAF6-binding | 228..233 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 264..390 | ||||
| Interaction with NTRK1. /evidence=ECO:0000250|UniProtKB:O08623 | 269..440 | ||||
| MAP1LC3B-binding. /evidence=ECO:0000269|PubMed:17580304 | 321..342 | ||||
| LIR | 336..341 | ||||
| Interaction with KEAP1. /evidence=ECO:0000269|PubMed:20452972 | 347..352 | ||||
| UBA_5 | 379..440 | CDD:318725 | |||
| sqst-3 | NP_507738.1 | ZZ_NBR1_like | 144..186 | CDD:239080 | 12/41 (29%) |
| Blue background indicates that the domain is not in the aligned region. | |||||