Protein Alignment VNN2 and CG32751

DIOPT Version :10

• Sequence 1: NP_004656.3
• Gene: VNN2 / 8875
• HGNCID: 12706
• Length: 520
• Species: Homo sapiens
• Sequence 2: NP_001284927.1
• Gene: CG32751 / 318189
• FlyBaseID: FBgn0052751
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 146/507 - (28%)
• Similarity: 215/507 - (42%)
• Gaps: 86/507 - (16%)

Human    55 NENIDILETAIKQAAEQGAR---IIVTPEDALYGWKFTRETVFPYLEDIPDPQVNWIPC-QDPHR 115
            ||..|.|...::....|.|.   |||.||..|   .....|.|     :|:|:....|| .||:.
  Fly    44 NELSDNLAGYLEIIQSQNATSTDIIVFPESTL---NSAGSTTF-----VPNPEDQINPCLSDPNA 100

Human   116 FGHTPVQARLSCLAKDNSIYVLANLGDKKPCNS--RDS-TCPPNGYFQYNTNVVYNTEGKLVARY 177
            ..:......|||.|::.|.|::.||.:|:.|..  .|: .|..||...:|||||::.:|.:|:||
  Fly   101 TYYEEFLVTLSCAARNASKYIVINLTEKQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVVSRY 165

Human   178 HKYHLYSEPQFNVPEKPELVTFNTAFG-RFGIFTCFDIFFYDPGVTLVKDFHVDTILFPTAWMNV 241
            .|.|||.||: |....|||.||.|.|| .||.|.||||.||.|...|:.:..:...::|..|.:.
  Fly   166 RKVHLYGEPK-NSTFLPELSTFETDFGVTFGHFICFDILFYTPAHQLIVEQGITDFVYPAMWFSQ 229

Human   242 LPLLT--------AIEFHSAWAMGMGVNLLVANTHHVSLNMTGSGIYAPNGPKVYHYDMKTELGK 298
            ||.||        |::....|:....||||.|......:..:|||||......:... |:.|.|:
  Fly   230 LPFLTVNGIFSSKAVQIQLGWSYANNVNLLAAGASDPIVGNSGSGIYHGRSGSLRSV-MRQESGE 293

Human   299 LLLSEVDSHPLSSLAYPTAVNWNAYATTIKPFPVQKNTFRGF-ISRDGF-NFT--ELFENAGNL- 358
                       .|:.......:.|.....:....|..|...| |.||.. |||  ||..:||.:
  Fly   294 -----------RSIYVARVPKYRAKRRMKRDLKRQVATSSSFNIKRDYLENFTSEELKIDAGKIG 347

Human   359 ----TVCQKELCCH--LSYRMLQKEENEV----YVLGAFTGLHGRRRRE--YWQVCTLLKCKTTN 411
                .:|....|||  |::|.|.|.....    |.:|.:.|....:|.:  |.:.|.:..|...:
  Fly   348 NLSQNLCHGGFCCHFDLAWRSLGKPSRNTSHYSYRVGIYEGWRNEKRLDVNYIRNCGVFTCSGNS 412

Human   412 LTTCG-------RPVETASTRFEMFSLSGTF--GTEY-VFPEVLLTE-IHLSPGKFE-----VLK 460
            :..||       ||:.|    |....:..|:  ..|: :||:.||.. :.|.|.:||     :.:
  Fly   413 IDDCGQLLPDIQRPLVT----FTHVEIRVTYPQSREFLLFPDTLLDNLLPLEPKQFEWSQKRISE 473

Human   461 DGRLV----NKNGSSGPILTVSLFGRWYTKDSLYS--------SCGTSNSAI 500
            :...|    .|:.....:||..::|.:|..:..:.        .||..|..|
  Fly   474 ESHQVRFALRKSLEVKHLLTFGIYGNYYNNECTFGVGTAEEQLECGYKNPKI 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VNN2	NP_004656.3	biotinidase_like	26..329	CDD:143591	92/289 (32%)
		Vanin_C	344..487	CDD:465946	45/178 (25%)
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	96/305 (31%)
		Vanin_C	324..503	CDD:465946	48/182 (26%)