Protein Alignment CCKBR and PK2-R2

DIOPT Version :10

• Sequence 1: NP_001350481.1
• Gene: CCKBR / 887
• HGNCID: 1571
• Length: 516
• Species: Homo sapiens
• Sequence 2: NP_731788.1
• Gene: PK2-R2 / 41638
• FlyBaseID: FBgn0038139
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 34
• Identity: 11/34 - (32%)
• Similarity: 14/34 - (41%)
• Gaps: 6/34 - (17%)

Human   141 ERISNPRINCMPASCKYNLEKTRPSGERQPPQYT 174
            |.|.|..|.      ||||..|....:|:...|:
  Fly    28 EFIQNQTIT------KYNLASTLEFQKRRLSLYS 55

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCKBR	NP_001350481.1	7tm_GPCRs	55..470	CDD:475119	11/34 (32%)
		TM helix 1	57..81	CDD:320645
		TM helix 2	90..112	CDD:320645
		TM helix 3	128..150	CDD:320645	4/8 (50%)
		TM helix 4	173..189	CDD:320645	1/2 (50%)
		TM helix 5	216..239	CDD:320645
		TM helix 6	401..423	CDD:320645
		TM helix 7	438..463	CDD:320645
PK2-R2	NP_731788.1	7tmA_capaR	69..355	CDD:320262
		TM helix 1	69..94	CDD:320262
		TM helix 2	101..127	CDD:320262
		TM helix 3	140..170	CDD:320262
		TM helix 4	182..204	CDD:320262
		TM helix 5	225..253	CDD:320262
		TM helix 6	275..305	CDD:320262
		TM helix 7	323..348	CDD:320262