Protein Alignment ST3GAL5 and SiaT

DIOPT Version :10

• Sequence 1: NP_003887.3
• Gene: ST3GAL5 / 8869
• HGNCID: 10872
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_523853.1
• Gene: SiaT / 37950
• FlyBaseID: FBgn0035050
• Length: 474
• Species: Drosophila melanogaster
• Alignment Length: 366
• Identity: 87/366 - (23%)
• Similarity: 130/366 - (35%)
• Gaps: 94/366 - (25%)

Human    83 LKLNYTTEECDMKKMHYVDPDHVKRAQKYAQQVLQKECRPKFAKTSMALLFE---HRYSVDLLPF 144
            ||::..|:.....|::.....|.:......||..|:..| .|.|..:..:.|   :.|:||..|.
  Fly   123 LKVSKNTKLTLSPKLYLCHDKHSELCHNKTQQFRQRIVR-AFEKAMVESVNESQANHYNVDYKPV 186

Human   145 VQKAPKDSEAESKY-----------------DPPFGFRKFSSKVQTLLELLPEHDLPEHLKAKTC 192
            .    .||..|..|                 |.||....|.       .|.|...|..::  |..
  Fly   187 F----GDSFEEQYYPSTCLVMEAGVRVLRRKDAPFNKLPFG-------RLFPRQKLFRNV--KDI 238

Human   193 RRCVVIGSGGILHGLELGHTLNQFDVVIRLNSAPVEGYSEHVGNKTTIR------MTYPEGAPLS 251
            :.|.::.|.|.|.|.:||..::..|:|:|.|.||.:|:...||:|||||      :|.||
  Fly   239 KTCAIVSSAGSLAGSKLGRFIDTHDIVMRFNHAPTQGHEVDVGSKTTIRVVNSQVVTKPE----- 298

Human   252 DLEYYSNDLFVAVLFKSVDFNWLQAMVKKETLPFWVR-----LFFWKQVAEKIPLQPKHFRILNP 311
                  .|...|.:|::|............||..|:.     ||             .::.:...
  Fly   299 ------FDFTRAPIFRNVTIAAWDPGKYNGTLEDWLTSADYDLF-------------SNYELYRR 344

Human   312 VIIKETAFDILQYSEPQS--RFWGR----------DKNVPTIGVIAVVLATHLCDEVSLAGFGYD 364
            ...|..||.|    :|.|  |.|..          .||.|:.|.|.:.|....|.:|....:
  Fly   345 RYPKSRAFLI----DPHSVWRLWQSLQMFAGNRPISKNPPSSGFIGLALLLPHCPQVDFVEY--- 402

Human   365 LNQPRTPL----HYFDSQCMAAMNFQTMHNVTTETKFLLKL 401
              .|.|.|    ||:..:..:|..|.:.|.:..|....|.:
  Fly   403 --VPSTRLNGRCHYYSKEMNSACTFGSWHPLAAEKLMALDM 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ST3GAL5	NP_003887.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		GT29_ST3GAL5	191..401	CDD:467711	59/236 (25%)
SiaT	NP_523853.1	GT29_ST6GAL1_2	199..469	CDD:467696	67/285 (24%)