Protein Alignment KSR1 and Ksr1

DIOPT Version :10

• Sequence 1: XP_047292941.1
• Gene: KSR1 / 8844
• HGNCID: 6465
• Length: 950
• Species: Homo sapiens
• Sequence 2: XP_011247072.1
• Gene: Ksr1 / 16706
• MGIID: 105051
• Length: 914
• Species: Mus musculus
• Alignment Length: 951
• Identity: 835/951 - (87%)
• Similarity: 864/951 - (90%)
• Gaps: 38/951 - (3%)

Human     1 MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRALQQCGQLQKLIDISIGSLRGLRTKCAVS 65
            |||||||||||||||||||||  |||:||||||.||||||||||||||||||||||||||||:||
Mouse     1 MDRAALRAAAMGEKKEGGGGG--AAADGGAGAAVSRALQQCGQLQKLIDISIGSLRGLRTKCSVS 63

Human    66 NDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNSYPRFSDWLYTFNVRPEVVQEIPRDL 130
            ||||||||||||||||:|||||:|.||||.|.:||.|||||||||||||.||||||||||||::|
Mouse    64 NDLTQQEIRTLEAKLVKYICKQQQSKLSVTPSDRTAELNSYPRFSDWLYIFNVRPEVVQEIPQEL 128

Human   131 TLDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEHKEDSSWSSLDARRESGSG 195
            ||||||||:|||.||.|||.|||.:||.|||.||||||||||||||||.||.|||.|| |:|..|
Mouse   129 TLDALLEMDEAKAKEMLRRWGASTEECSRLQQALTCLRKVTGLGGEHKMDSGWSSTDA-RDSSLG 192

Human   196 PSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASDSPTPSFSEGLSDTCIPLHASGRL 260
            |..|.||:           |||||.|.|||||||||||||||||.|..||||||:|||||.||||
Mouse   193 PPMDMLSS-----------LGRAGASTQGPRSISVSALPASDSPVPGLSEGLSDSCIPLHTSGRL 246

Human   261 TPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVSS 325
            ||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||:.
Mouse   247 TPRALHSFITPPTTPQLRRHAKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVTP 311

Human   326 MRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPA 390
            |:|:|.|||||:|||||||||||||||||||||||:|||||||||||||||||||||||||||||
Mouse   312 MKFELPHGSPQLVRRDIGLSVTHRFSTKSWLSQVCNVCQKSMIFGVKCKHCRLKCHNKCTKEAPA 376

Human   391 CRISFLPLTRLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSST 455
            |||:||||.||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Mouse   377 CRITFLPLARLRRTESVPSDINNPVDRAAEPHFGTLPKALTKKEHPPAMN-LDSSSNPSSTTSST 440

Human   456 PSSPAPFPTSSNPSSATTPPNPSPGQRDSRFNFPAAYFIHHRQQFIFPVPSAGHCWKCLLIAESL 520
            |||||||.|||||||||||||||||||||||:||||||||||||||||
Mouse   441 PSSPAPFLTSSNPSSATTPPNPSPGQRDSRFSFPAAYFIHHRQQFIFP----------------- 488

Human   521 KENAFNISAFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDD-EDEVDDLPSS 584
                 :|||.:.||||...||.||||||||.|||..|||||||||||||||||| ||||||||||
Mouse   489 -----DISACSQAAPLSSTADSTRLDDQPKTDVLGVHEAEAEEPEAGKSEAEDDEEDEVDDLPSS 548

Human   585 RRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQD 649
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   549 RRPWRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQD 613

Human   650 HLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIA 714
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   614 HLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIA 678

Human   715 QEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYL 779
            ||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||
Mouse   679 QEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERRENQLKLSHDWLCYL 743

Human   780 APEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLT 844
            ||||||||.||:|||||||||||||||||||||||||||||.|:|.|||.|||||||||::|||.
Mouse   744 APEIVREMIPGRDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAEALIWQIGSGEGVRRVLA 808

Human   845 SVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSADRWRSRYYGKGR 909
            ||||||||.|||||||||||||||||||||||||:||||||||||||||||||||||||||||||
Mouse   809 SVSLGKEVGEILSACWAFDLQERPSFSLLMDMLERLPKLNRRLSHPGHFWKSADRWRSRYYGKGR 873

Human   910 YGHPDFKSSCPILEEYINSSKVVPRFERFGLGVLESSNPKM 950
            |||||||:|||:||||||||||:|||||||||.|||.||||
Mouse   874 YGHPDFKNSCPVLEEYINSSKVMPRFERFGLGTLESGNPKM 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KSR1	XP_047292941.1	SAM_KSR1_N	41..94	CDD:466555	48/52 (92%)
		SAM_KSR1	102..168	CDD:463916	54/65 (83%)
		C1_KSR1	346..392	CDD:410422	44/45 (98%)
		STKc_KSR1	612..890	CDD:271054	265/277 (96%)
Ksr1	XP_011247072.1	SAM_KSR1_N	39..92	CDD:466555	48/52 (92%)
		SAM_KSR1	100..166	CDD:463916	54/65 (83%)
		C1_KSR1	332..378	CDD:410422	44/45 (98%)
		STKc_KSR1	576..854	CDD:271054	265/277 (96%)