Protein Alignment HCAR3 and AstC-R1

DIOPT Version :9

• Sequence 1: NP_006009.2
• Gene: HCAR3 / 8843
• HGNCID: 16824
• Length: 387
• Species: Homo sapiens
• Sequence 2: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 95/379 - (25%)
• Similarity: 171/379 - (45%)
• Gaps: 51/379 - (13%)

Human    16 KNCCVFRDDFIAKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICL 80
            ::|...|:.|.......:.|...|.||.||.|.:::.....|....:.|::.||||||...:|.:
  Fly    66 QHCIATRNSFADLFTVVLYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVADECFLIGI 130

Human    81 PFVMDYYVRRSDWKFGDIPCRLVLFMFAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNWTAA 145
            ||:: |.:|...|:||:..|:..:...::....|.|||.:::.|||..|.||..:....:...|.
  Fly   131 PFLL-YTMRICSWRFGEFMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAK 194

Human   146 IISCLLWGITVGLTVHLLKKKLLIQNGTANVCISFSICHTFRWHEA------------MFLLEFF 198
            ::|.:.|..:..|.:.::.....::....   |::| |: ..|.:|            .|.|.|.
  Fly   195 VVSAIAWSTSAVLMLPVILYASTVEQEDG---INYS-CN-IMWPDAYKKHSGTTFILYTFFLGFA 254

Human   199 LPLGIILFCSARIIWSLR----------QRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIH 253
            .||..||.....:|..||          :.:...|.|:.|   .::.|..|:::|:||..:.::.
  Fly   255 TPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTR---LVLTVISVYILCWLPHWISQVA 316

Human   254 IFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSF-PNFFSTLINRCLQRKI 317
               |:|::..|. ::.|...|.|.:..:..|.||.::|::|.|.|.:| .:||...  .|:.::
  Fly   317 ---LIHSNPAQR-DLSRLEILIFLLLGALVYSNSAVNPILYAFLSENFRKSFFKAF--TCMNKQ- 374

Human   318 TGEPDNNRSTSVE---LTGDPNKTRGAPEALIANSGE--PWSPSYLGPTSNNHS 366
                |.|....:|   .|...:|.||..:.|:.::.:  |..|...|   ||:|
  Fly   375 ----DINAQLQLEPSVFTKQGSKKRGGSKRLLTSNPQIPPLLPLNAG---NNNS 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HCAR3	NP_006009.2	7tm_1	44..294	CDD:278431	67/271 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	319..343		7/26 (27%)
AstC-R1	NP_649040.2	7tm_4	88..368	CDD:304433	76/292 (26%)
		7tm_1	94..353	CDD:278431	67/271 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910