Protein Alignment CDKL1 and SGV1

DIOPT Version :9

• Sequence 1: XP_005268214.1
• Gene: CDKL1 / 8814
• HGNCID: 1781
• Length: 358
• Species: Homo sapiens
• Sequence 2: NP_015487.1
• Gene: SGV1 / 856290
• SGDID: S000006365
• Length: 657
• Species: Saccharomyces cerevisiae
• Alignment Length: 356
• Identity: 112/356 - (31%)
• Similarity: 163/356 - (45%)
• Gaps: 76/356 - (21%)

Human     5 YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLE 69
            |.:..|:|:|::|.|:|..:.:|.:.||:||.:.|.:..:....|.|||.:||:|.|.|::.|:|
Yeast    60 YREDEKLGQGTFGEVYKGIHLETQRQVAMKKIIVSVEKDLFPITAQREITILKRLNHKNIIKLIE 124

Human    70 VF---------RRKRRLHLVF----------------------EYCDHTVLHELDRYQRGVPEHL 103
            :.         .....||..|                      |.||
Yeast   125 MVYDHSPDITNAASSNLHKSFYMILPYMVADLSGVLHNPRINLEMCD------------------ 171

Human   104 VKSITWQTLQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLL------------TGPS 156
            :|::..|.|:.:|:.|....:|||:|..||||..:.|:||.|||.|||.            .|..
Yeast   172 IKNMMLQILEGLNYIHCAKFMHRDIKTANILIDHNGVLKLADFGLARLYYGCPPNLKYPGGAGSG 236

Human   157 DYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGD 221
            ..||..|.|||||:|||::||.||...||:|.:||||||.....|:..||:|:||.::|.|.||
Yeast   237 AKYTSVVVTRWYRAPELVLGDKQYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLLG- 300

Human   222 LIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKFPN-ISYPALGLLKGCLHMDPTQRLTCEQLLHH 285
             .|..:. ::..:|..|.::........|..:|.. :|...|..|...|.:||.:|||.....||
Yeast   301 -TPTEED-WAVARYLPGAELTTTNYKPTLRERFGKYLSETGLDFLGQLLALDPYKRLTAMSAKHH 363

Human   286 PYFENIREIEDLAKEHNKPTRK-TLRKSRKH 315
            |:|          ||...|:.| ||.....|
Yeast   364 PWF----------KEDPLPSEKITLPTEESH 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKL1	XP_005268214.1	STKc_CDKL1_4	3..288	CDD:270837	104/326 (32%)
SGV1	NP_015487.1	STKc_BUR1	50..366	CDD:270849	104/326 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910