Protein Alignment CDKL1 and Cdkl1

DIOPT Version :10

• Sequence 1: NP_004187.3
• Gene: CDKL1 / 8814
• HGNCID: 1781
• Length: 357
• Species: Homo sapiens
• Sequence 2: NP_001020292.1
• Gene: Cdkl1 / 314198
• RGDID: 1305080
• Length: 352
• Species: Rattus norvegicus
• Alignment Length: 357
• Identity: 315/357 - (88%)
• Similarity: 333/357 - (93%)
• Gaps: 5/357 - (1%)

Human     1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVN 65
            |||||||||||||||||||||||||||||||||:|||:||||||||||||||||||||||||||:
  Rat     1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKHPNLVS 65

Human    66 LLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIHRDVKPE 130
            ||||||||||||||||||.||||||||||||||||.|||:|||||||||||||||||||||||||
  Rat    66 LLEVFRRKRRLHLVFEYCHHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKHNCIHRDVKPE 130

Human   131 NILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 195
            ||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||
  Rat   131 NILITKHSVIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAEL 195

Human   196 LSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKFPNISYPA 260
            |||||||||||||||||||||||||||||||||||.||||||||||||||||.||||||||||.|
  Rat   196 LSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKIPDPEDMETLELKFPNISYSA 260

Human   261 LGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKEHNKPTRKTLRKSRKHHCFTETSKLQY 325
            ||.|||||||||.:||||||||.||||::||::.:||:.|:||||||||:||||     .:.||:
  Rat   261 LGFLKGCLHMDPAERLTCEQLLQHPYFDSIRDVGELARPHDKPTRKTLRQSRKH-----LTGLQH 320

Human   326 LPQLTGSSILPALDNKKYYCDTKKLNYRFPNI 357
            |||||.||:|||||.|||:|.|:..||.||||
  Rat   321 LPQLTSSSVLPALDRKKYHCGTRNFNYHFPNI 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKL1	NP_004187.3	STKc_CDKL1_4	2..287	CDD:270837	270/284 (95%)
		[NKR]KIAxRE	45..51		5/5 (100%)
Cdkl1	NP_001020292.1	STKc_CDKL1_4	2..287	CDD:270837	270/284 (95%)
		[NKR]KIAxRE	45..51		5/5 (100%)