Protein Alignment GALR2 and AstA-R1

DIOPT Version :9

• Sequence 1: NP_003848.1
• Gene: GALR2 / 8811
• HGNCID: 4133
• Length: 387
• Species: Homo sapiens
• Sequence 2: NP_524700.1
• Gene: AstA-R1 / 44126
• FlyBaseID: FBgn0266429
• Length: 394
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 106/295 - (35%)
• Similarity: 166/295 - (56%)
• Gaps: 20/295 - (6%)

Human    25 AVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLD 89
            :.|||:.|.:|...|.:||.||:.|::...|..|||||.|:||.|:|:.|::.||||.||.|.|.
  Fly    74 STIVPVFFGIIGFAGLLGNGLVILVVVANQQMRSTTNLLIINLAVSDILFVIFCVPFTATDYVLP 138

Human    90 GWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIW---- 150
            .|.||::.||.|.::|.:|.|.|.:||..:|.||:||:.:|:.|..|||.|||..||...|
  Fly   139 EWPFGNVWCKFVQYMIVVTCHCSVYTLVLMSFDRFLAVVHPVTSMSLRTERNATLAIMCAWITIV 203

Human   151 ----GLSLLFSGPYLSYYRQSQLANLTVC-----HPAWSAPRRRAMDICTFVFSYLLPVLVLGLT 206
                .::|..|.....|:..:.    |.|     ...||..   ...:..|:.||:.|:.::...
  Fly   204 TTAIPVALSHSVRIYQYHGNAG----TACVFSTEEEIWSLV---GFQVSFFLSSYVAPLTLICFL 261

Human   207 YARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATY 271
            |...|..||::.......:.:|:.||:||||:::|...|.:||:|.|.:::......:..:..:.
  Fly   262 YMGMLARLWKSAPGCKPSAESRKGKRRVTRMVVVVVLAFAICWLPIHVILVLKALNLYGGSHLSV 326

Human   272 ALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTI 306
            .::|:||:|:|.|||:|||:||.:|.:|||.||.:
  Fly   327 IIQIISHVVAYTNSCINPILYAFLSDNFRKAFRKV 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALR2	NP_003848.1	7tm_4	32..>177	CDD:304433	61/157 (39%)
		7tm_1	42..292	CDD:278431	92/262 (35%)
AstA-R1	NP_524700.1	7tm_4	83..>240	CDD:304433	62/160 (39%)
		7tm_1	91..347	CDD:278431	92/262 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147279
Domainoid	1	1.000	176	1.000	Domainoid score	I3617
eggNOG	1	0.900	-	-		E33208_3B9CW
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2863
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3667
Isobase	1	0.950	-	0	Normalized mean entropy	S5404
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm9822
orthoMCL	1	0.900	-	-		OOG6_105726
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3950
SonicParanoid	1	1.000	-	-		X1132
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.680