Protein Alignment GALR2 and AstA-R2

DIOPT Version :9

• Sequence 1: NP_003848.1
• Gene: GALR2 / 8811
• HGNCID: 4133
• Length: 387
• Species: Homo sapiens
• Sequence 2: NP_001263042.1
• Gene: AstA-R2 / 43393
• FlyBaseID: FBgn0039595
• Length: 357
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 94/297 - (31%)
• Similarity: 156/297 - (52%)
• Gaps: 32/297 - (10%)

Human    27 IVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGW 91
            ||...|.:|.:.|..||.||:.|::......|||||.|:||..|||.|::.|:||.||.|.:..|
  Fly    40 IVGFFFGVIAITGFFGNLLVILVVVFNNNMRSTTNLMIVNLAAADLMFVILCIPFTATDYMVYYW 104

Human    92 VFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLF 156
            .:|...|::|.:||.:|..||.:||..:|:||:||:.:|:.||.:||....|.||..:|.:.|:.
  Fly   105 PYGRFWCRSVQYLIVVTAFASIYTLVLMSIDRFLAVVHPIRSRMMRTENITLIAIVTLWIVVLVV 169

Human   157 SGPYLSYYRQSQLANLTVCHPA---WSAPRRRAMDICT----------------FVFSYLLPVLV 202
            |.|            :...|..   :.|.:.....:||                |:.|||||:::
  Fly   170 SVP------------VAFTHDVVVDYDAKKNITYGMCTFTTNDFLGPRTYQVTFFISSYLLPLMI 222

Human   203 LGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLT 267
            :...|.|.:..|||....|.....::|.:::|||::::|...|...|:|...::|..........
  Fly   223 ISGLYMRMIMRLWRQGTGVRMSKESQRGRKRVTRLVVVVVIAFASLWLPVQLILLLKSLDVIETN 287

Human   268 RAT-YALRILSHLVSYANSCVNPIVYALVSKHFRKGF 303
            ..| ..:::.:..::|::||:||::||.:|::|||.|
  Fly   288 TLTKLVIQVTAQTLAYSSSCINPLLYAFLSENFRKAF 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GALR2	NP_003848.1	7tm_4	32..>177	CDD:304433	54/144 (38%)
		7tm_1	42..292	CDD:278431	82/269 (30%)
AstA-R2	NP_001263042.1	7tm_4	47..>164	CDD:304433	49/116 (42%)
		7tm_1	55..313	CDD:278431	82/269 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147276
Domainoid	1	1.000	176	1.000	Domainoid score	I3617
eggNOG	1	0.900	-	-		E33208_3B9CW
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I3667
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1294084at2759
OrthoFinder	1	1.000	-	-		FOG0000972
OrthoInspector	1	1.000	-	-		mtm9822
orthoMCL	1	0.900	-	-		OOG6_105726
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1132
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.700