DRSC/TRiP Functional Genomics Resources

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Protein Alignment IL18RAP and LOC101882195

DIOPT Version :9

Sequence 1:NP_001380415.1 Gene:IL18RAP / 8807 HGNCID:5989 Length:599 Species:Homo sapiens
Sequence 2:XP_017210043.1 Gene:LOC101882195 / 101882195 -ID:- Length:409 Species:Danio rerio


Alignment Length:372 Identity:71/372 - (19%)
Similarity:123/372 - (33%) Gaps:115/372 - (30%)


- Green bases have known domain annotations that are detailed below.


Human   105 IQDKCTL------HFLTPG--------------------VNNSGSY------ICRPKMIKSPYD- 136
            ::|.|.:      .|.|||                    ::||.|:      :.....::...| 
Zfish    30 LKDSCVVVGPEIPDFHTPGEAVIIRFPFLEDAIRYRRLRLDNSSSFHVNHTSLSNQSSLRLHRDR 94

Human   137 VACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSIS-------------------------CP 176
            |....:.:|.:..||..|..||.:.:.|... .|||||                         ||
Zfish    95 VKLSGRGVLLLPGQTTDSGTYSYTLRSDTFC-LTGSISITVSADLNTTVMPFSTYAGADTRIICP 158

Human   177 SLSCQSDAQSPAVTWYKN----------GKLLSVERSNRIVVDEVYDYHQGTYVCDYT------Q 225
            .|...:..|:  ..|:||          |: .|:|:...:.:..:....:|.|.|..|      |
Zfish   159 HLQYYTRTQN--ARWHKNFESRALPVGRGR-YSIEKGIILAIRNISVEDEGYYTCRLTVVVNNAQ 220

Human   226 SDTVSSWTV--------------RAVVQVRTIVGDTKLKPDILDPVEDT-LEVELGKPLTISCKA 275
            .:...:|.|              |..|....:.......|..:.||..: :|...|..|.:.|..
Zfish   221 YNVSRTWRVHVTENAAPPTVTSNRPPVTSSAVTSSGISSPHFVSPVNGSFIESRSGSQLLLQCVV 285

Human   276 RFGFERVFNP---VIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVC 337
                 ...||   .:.|.|..:..|.......|...::.:.|..:|..:::..:.:.|...:..|
Zfish   286 -----SAVNPSSAELTWLINGNTPEHSHLAGRALQSQNRITDLTVEVQLLISILHEEDHGTELSC 345

Human   338 FVQNSIGNTTQSVQLKEKRGVVLLYILL---GTIGTLVAVLAASALL 381
            ..:|           :|::..||.||.|   |:..::.||::...||
Zfish   346 RWRN-----------QEQKLEVLTYIRLTDSGSWWSVAAVISCCFLL 381

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IL18RAPNP_001380415.1 Ig_6 100..155 CDD:408247 14/82 (17%)
Ig 162..>221 CDD:416386 18/93 (19%)
Ig strand A 162..166 CDD:409353 1/3 (33%)
Ig strand B 171..175 CDD:409353 4/28 (14%)
Ig strand C 188..193 CDD:409353 1/4 (25%)
Ig strand C' 196..198 CDD:409353 0/1 (0%)
Ig strand E 204..209 CDD:409353 0/4 (0%)
Ig 251..354 CDD:416386 18/106 (17%)
Ig strand A 251..254 CDD:409353 1/2 (50%)
Ig strand A' 262..265 CDD:409353 1/2 (50%)
Ig strand B 267..276 CDD:409353 2/8 (25%)
Ig strand C 285..290 CDD:409353 1/7 (14%)
Ig strand D 300..308 CDD:409353 1/7 (14%)
Ig strand E 315..323 CDD:409353 1/7 (14%)
Ig strand F 334..340 CDD:409353 1/5 (20%)
Ig strand G 344..350 CDD:409353 0/5 (0%)
TIR 419..559 CDD:396246
LOC101882195XP_017210043.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D417685at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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