Protein Alignment SUCLG1 and LSC1

DIOPT Version :10

• Sequence 1: NP_003840.2
• Gene: SUCLG1 / 8802
• HGNCID: 11449
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_014785.3
• Gene: LSC1 / 854310
• SGDID: S000005668
• Length: 329
• Species: Saccharomyces cerevisiae
• Alignment Length: 306
• Identity: 182/306 - (59%)
• Similarity: 223/306 - (72%)
• Gaps: 4/306 - (1%)

Human    43 YTASRQHLYVDKNTKIICQGFTGKQGTFHSQQALEYGTKLVGGTTPGKGGQTHLGLPVFNTVKEA 107
            |..:.::|.:.|:||:|.|||||||||||:..:.||||.:||||.|.|.||||||.|||.:||:|
Yeast    24 YDKTIKNLLLPKDTKVIFQGFTGKQGTFHASISQEYGTNVVGGTNPKKAGQTHLGQPVFASVKDA 88

Human   108 KEQTGATASVIYVPPPFAAAAINEAIEAEIPLVVCITEGIPQQDMVRVKHKLLRQEKTRLIGPNC 172
            .::||||||.|:||||.|||||.|:|||||||.|||||||||.||:.:...|..|:||||:||||
Yeast    89 IKETGATASAIFVPPPIAAAAIKESIEAEIPLAVCITEGIPQHDMLYIAEMLQTQDKTRLVGPNC 153

Human   173 PGVINPG-ECKIGIMPGHIHKKGRIGIVSRSGTLTYEAVHQTTQVGLGQSLCVGIGGDPFNGTDF 236
            ||:|||. :.:|||.|..|.:.|:|||:|||||||||||.|||:..|||||.:|:|||.|.||||
Yeast   154 PGIINPATKVRIGIQPPKIFQAGKIGIISRSGTLTYEAVQQTTKTDLGQSLVIGMGGDAFPGTDF 218

Human   237 IDCLEIFLNDSATEGIILIGEIGGNAEENAAEFLKQHN-SGPNSKPVVSFIAGLTA--PPGRRMG 298
            ||.|::||.|..|||||::|||||.||..||:|||::| |.....||.|||||..|  ..|.|||
Yeast   219 IDALKLFLEDETTEGIIMLGEIGGKAEIEAAQFLKEYNFSRSKPMPVASFIAGTVAGQMKGVRMG 283

Human   299 HAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRK 344
            |:|||:.|....|:.|..||:..||.|..||..||..:..:|.|.|
Yeast   284 HSGAIVEGSGTDAESKKQALRDVGVAVVESPGYLGQALLDQFAKFK 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SUCLG1	NP_003840.2	PTZ00187	19..344	CDD:240307	181/304 (60%)
LSC1	NP_014785.3	SucD	30..321	CDD:439844	178/290 (61%)