DRSC/TRiP Functional Genomics Resources

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Protein Alignment PEX11A and Pex11ab

DIOPT Version :10

Sequence 1:NP_003838.1 Gene:PEX11A / 8800 HGNCID:8852 Length:247 Species:Homo sapiens
Sequence 2:NP_611071.1 Gene:Pex11ab / 36758 FlyBaseID:FBgn0034058 Length:241 Species:Drosophila melanogaster


Alignment Length:245 Identity:80/245 - (32%)
Similarity:127/245 - (51%) Gaps:8/245 - (3%)


- Green bases have known domain annotations that are detailed below.


Human     1 MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVV 65
            ||...:..||..|||::.|..||....:...||.......:|...|.:|..:||.||..|.|..|
  Fly     1 MDQLVQLNNQAGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCV 65

Human    66 HAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYS 130
            .......::||..||..|:.|||:.|::.::...|..||:...|||: :|.::|...|..::.:|
  Fly    66 DVFYGALKTIHHPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLTA-VNAKRWSNIANKYWLFS 129

Human   131 LLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEE-ETEWLQSFLLLLFRSLKQHPPL 194
            ::::|.||.||| |::..:....:|...|..:.|...:..|: :...|||::|     ::.|..:
  Fly   130 IIMNLCRDFYEI-LRVLDLHRSGSKSGISRCRIPASINSPEDFKRLALQSYVL-----MQGHKDI 188

Human   195 LLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKL 244
            ::|||||.||...||..||.....|..|||.|.:||:||:..:..|:.||
  Fly   189 VVDTVKNACDFFIPLTALGYTSLTPRTIGLLGAISSLAGLWALLEPRAKL 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PEX11ANP_003838.1 PEX11 1..237 CDD:398979 77/236 (33%)
Required for homodimerization, interaction with PEX11G, and peroxisomal localization. /evidence=ECO:0000269|PubMed:20826455 220..239 8/18 (44%)
Pex11abNP_611071.1 PEX11 1..232 CDD:398979 77/237 (32%)

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