Protein Alignment PEX11B and Pex11ab

DIOPT Version :10

• Sequence 1: NP_003837.1
• Gene: PEX11B / 8799
• HGNCID: 8853
• Length: 259
• Species: Homo sapiens
• Sequence 2: NP_611071.1
• Gene: Pex11ab / 36758
• FlyBaseID: FBgn0034058
• Length: 241
• Species: Drosophila melanogaster
• Alignment Length: 264
• Identity: 84/264 - (31%)
• Similarity: 138/264 - (52%)
• Gaps: 29/264 - (10%)

Human     1 MDAWVRFSAQSQARERLCRAAQYACSLLGHALQRHGASPELQKQIRQLESHLSLGRKLLRLGNSA 65
            ||..|:.:.|:..|:::.|..|||...:..:|:...::|.|....:.:|..||..|||||.|...
  Fly     1 MDQLVQLNNQAGGRDKIARLIQYASRAMWDSLESANSNPALVDNFKTVEYILSTFRKLLRFGKCV 65

Human    66 DALESAKRAVHLSDVVLRFCITVSHLNRALYFACDNVLWAGKSGLAPRVDQEKWAQRSFRYYLFS 130
            |....|.:.:|..|:.:|..:|:|.|:::|:...|:.||..::||. .|:.::|:..:.:|:|||
  Fly    66 DVFYGALKTIHHPDLNIRVTLTLSKLSQSLFLFADHFLWLARTGLT-AVNAKRWSNIANKYWLFS 129

Human   131 LIMNLSRDAYEIRLLMEQESSACSRRLKGSGGG-----VPGGSETGGLGGPGTPGGGLPQLALKL 190
            :||||.||.|||..:::...|       ||..|     :|....:             |:...:|
  Fly   130 IIMNLCRDFYEILRVLDLHRS-------GSKSGISRCRIPASINS-------------PEDFKRL 174

Human   191 RLQVLLLARVLRGHPPLLLDVVRNACDLFIPLDKLGLWRCGPGIVGLCGLVSSILSILTLIYPWL 255
            .||..:|   ::||..:::|.|:||||.||||..||.....|..:||.|.:||:..:..|:.|..
  Fly   175 ALQSYVL---MQGHKDIVVDTVKNACDFFIPLTALGYTSLTPRTIGLLGAISSLAGLWALLEPRA 236

Human   256 RLKP 259
            :|.|
  Fly   237 KLTP 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX11B	NP_003837.1	PEX11	1..250	CDD:398979	80/253 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..176		4/23 (17%)
		Interaction with PEX19, PEX11G and FIS1 and peroxisome targeting. /evidence=ECO:0000269|PubMed:10704444, ECO:0000269|PubMed:20826455	211..259		20/47 (43%)
Pex11ab	NP_611071.1	PEX11	1..232	CDD:398979	80/254 (31%)