| Sequence 1: | NP_001362342.1 | Gene: | MPDZ / 8777 | HGNCID: | 7208 | Length: | 2103 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001246755.1 | Gene: | bbg / 39583 | FlyBaseID: | FBgn0087007 | Length: | 2637 | Species: | Drosophila melanogaster |
| Alignment Length: | 2198 | Identity: | 459/2198 - (20%) |
|---|---|---|---|
| Similarity: | 760/2198 - (34%) | Gaps: | 639/2198 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Human 100 GNLEALTGPGIP---------HINGKPACDEFDQLIKNMAQGRHVEVFELLKPPS---GGLGFSV 152
Human 153 VGLRSENRGELGIFVQEIQEGSVAH-RDGRLKETDQILAINGQALDQTITHQ-QAISI------- 208
Human 209 LQKAKDTVQLVIARGSLPQLVSPIVSRSPSAASTI---------------SAHSNPVHWQHMETI 258
Human 259 ELVNDGSGLGFGIIGGKATG--VIVKTILPGGVADQHGRLCSGDHILKIGD-TDLAGMSSEQ--V 318
Human 319 AQVLRQCGNRVKL-------MIARG--AIEERTAPTALGITLSSSPTSTPELRVDASTQKGEESE 374
Human 375 TFDVELTKNVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGF 439
Human 440 TNQQAVEVLRHTGQTVL-LTLMRRGMKQEAE--LMSREDVTKDADLSPVNASIIK-ENYEKDEDF 500
Human 501 -LSSTRNTNILPTEEEGYPLLSAEIEEIEDAQ------KQEAALLTKWQRIMGINYEIVVAHVSK 558
Human 559 FSENSGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGE----NHQDV---- 615
Human 616 --VNILKELPIEVTMVCCRRTVPPTT------------------QSELDSLDLCDIELTEKP-HV 659
Human 660 DLG--------------------------------------------------------EFIGSS 668
Human 669 ETEDPVLAMTDAGQSTEEVQ--APLAMWEAGI-QHIELEKGSKGLGFSILDYQD--PIDPASTVI 728
Human 729 IIRSLVPGGIAEKDGRLLPGDRLMF-----VNDVNLENSSLEEAVEALKGAPSGTVRIGVAKPLP 788
Human 789 LSPEEGYVSAK-----------------EDSFLYPPHSCEEAGLADKPLFRADLALVGTNDADLV 836
Human 837 DESTFESPYSPENDSIYSTQASILSLHGSSCG--DGLNYGSSLPSSPPKDVIENSCDPVLDLHMS 899
Human 900 LEELYTQNLLQRQDENTPSVDISMGPASGFTINDYTPANAIEQQYECENTIVWTESHLPSEVISS 964
Human 965 AELP--SVLPDSAGKGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGMTVSANKD 1027
Human 1028 GLGM----------IVRSIIHGGAISRDGRIAIGD-----------------------CILSINE 1059
Human 1060 E--------STISVTNAQARAMLRRHS--LI-------GPDIKITYVPAEHLEEF--KISLGQQS 1105
Human 1106 GRVMALD-IFSSYTGRDIP---ELPERE---------------EGEGEESELQNTAYSNWNQPRR 1151
Human 1152 VELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFI---KHVLE---DSPAGKNGTLKPGDRIVE 1210
Human 1211 VDGMDLRDA----SHEQAVE------AIRKAGNPVVFMVQSIINRPRKSPLPSLLHNLYPKYNFS 1265
Human 1266 STNPFADSLQINADKAPSQSESEPEKAPL-------CSVPPPPPSAFAEMGSDHTQSSASKISQD 1323
Human 1324 VDKEDEFGYSWKNIRERYGTLTGELHMIELEKGHSGLGLSLAGNKDRSRMSVFIVGIDPNGAAGK 1388
Human 1389 DGRLQIADELLE---INGQILYGRSHQNASSIIKCAPSKVKIIFIRNKDAVNQMAVCPGNAVEPL 1450
Human 1451 PSNSENLQNKELGYHRFSLYSKPRQSSSHLVYLCSQLIAVQLHL-----TEPTVTTSDAAVDLS- 1509
Human 1510 ---------SFKNVQHLELPKDQGGLGIAISEEDTLSGVIIKSLTEHGVAATDGRLKVG-DQILA 1564
Human 1565 VDDEIVVGYPI----------EKFISLLKTAKMTVKLTIHAENPDSQAVPSAAGAASGEKKNSSQ 1619
Human 1620 SLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPGCETTIEISKGRTGLGLSIVGGSDTLL 1684
Human 1685 GAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHDEAINVLRQTPQRVRLTLYRDE---- 1745
Human 1746 -APYKEEEVCDTLTIELQKKPGKGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVN 1809
Human 1810 GEDVRNATQEAVAALLKCSLGTVTLEVGRIKAGPFHSE-----------RRPSQSSQVSEGSLSS 1863
Human 1864 FTFPLSGSSTSESLESSSK-KNALASEIQ-----------GLRTVEMKKGPTDS--LGISIAGGV 1914
Human 1915 GSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLK 1967 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MPDZ | NP_001362342.1 | PDZ_signaling | 2019..2102 | CDD:238492 | |
| L27_2 | 6..63 | CDD:312549 | |||
| PDZ_signaling | 139..221 | CDD:238492 | 23/93 (25%) | ||
| PDZ_signaling | 257..334 | CDD:238492 | 15/88 (17%) | ||
| PDZ | 374..463 | CDD:214570 | 13/89 (15%) | ||
| PDZ_signaling | 560..629 | CDD:238492 | 16/78 (21%) | ||
| PDZ_signaling | 698..784 | CDD:238492 | 21/93 (23%) | ||
| PDZ_signaling | 1006..1076 | CDD:238492 | 15/110 (14%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1121..1140 | 7/36 (19%) | |||
| PDZ_signaling | 1149..1240 | CDD:238492 | 22/106 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1278..1324 | 12/52 (23%) | |||
| PDZ | 1347..1433 | CDD:214570 | 16/88 (18%) | ||
| PDZ_signaling | 1514..1593 | CDD:238492 | 13/89 (15%) | ||
| MPDZ_u10 | 1595..1659 | CDD:374710 | 12/63 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1600..1645 | 9/44 (20%) | |||
| PDZ | 1660..1744 | CDD:214570 | 30/83 (36%) | ||
| PDZ_signaling | 1758..1836 | CDD:238492 | 15/77 (19%) | ||
| PDZ_signaling | 1893..1978 | CDD:238492 | 33/77 (43%) | ||
| bbg | NP_001246755.1 | PDZ_signaling | 90..177 | CDD:238492 | |
| ATP-synt_B | <1084..>1109 | CDD:304375 | 8/30 (27%) | ||
| PDZ_signaling | 2331..2413 | CDD:238492 | 31/87 (36%) | ||
| PDZ_signaling | 2553..2634 | CDD:238492 | 33/76 (43%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG3528 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||