DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RAB11A and Rab11

DIOPT Version :9

Sequence 1:	NP_004654.1	Gene:	RAB11A / 8766	HGNCID:	9760	Length:	216	Species:	Homo sapiens
Sequence 2:	NP_477170.1	Gene:	Rab11 / 42501	FlyBaseID:	FBgn0015790	Length:	214	Species:	Drosophila melanogaster

Alignment Length:	214	Identity:	183/214 - (85%)
Similarity:	193/214 - (90%)	Gaps:	0/214 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIW 65
            ||.|:||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
  Fly     1 MGAREDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIW 65

Human    66 DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRH 130
            |||||||||||||||||||||||||||||||||||||||||:|||||||.|||||||||||||||
  Fly    66 DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRH 130

Human   131 LRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNV 195
            ||:||||||:.|||:|||||||||||||||||.|||.|||||||||||||:.|..|.|:...:||
  Fly   131 LRSVPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNV 195

Human   196 VPIHVPPTTENKPKVQCCQ 214
            .||.|.||.....:.||||
  Fly   196 EPIDVKPTVTADVRKQCCQ 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RAB11A	NP_004654.1	Rab11_like	9..173	CDD:206660	154/163 (94%)
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	154/163 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144707
Domainoid	1	1.000	302	1.000	Domainoid score	I1400
eggNOG	1	0.900	-	-		E2759_KOG0087
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37903
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2182
Isobase	1	0.950	-	0	Normalized mean entropy	S128
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133775at2759
OrthoFinder	1	1.000	-	-		FOG0000259
OrthoInspector	1	1.000	-	-		otm40982
orthoMCL	1	0.900	-	-		OOG6_100582
Panther	1	1.100	-	-	LDO	PTHR47979
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5006
SonicParanoid	1	1.000	-	-		X277
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.740