Protein Alignment PABPC4 and shep

DIOPT Version :10

• Sequence 1: NP_001129125.1
• Gene: PABPC4 / 8761
• HGNCID: 8557
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_001246636.1
• Gene: shep / 38605
• FlyBaseID: FBgn0052423
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 373
• Identity: 90/373 - (24%)
• Similarity: 142/373 - (38%)
• Gaps: 109/373 - (29%)

Human   100 NVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGML 162
            |::|:.|.:...:|.|.:..:.:|.|:|.|.:.|:  |..|||.||.||....|:.|::.:.|
  Fly   244 NLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQG-- 306

Human   163 LNDRKVFVGRFKSRKEREAELGAKAKEF--TNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRD 225
                          |..:|:: ||.:|.  ||:||.|......:..|:.:.|::|:.:|.:::||
  Fly   307 --------------KGVQAQM-AKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRD 356

Human   226 PNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGK-----IIFVGRAQKKVERQAELKRKFEQLKQ 285
            ....|||.||...|..|...:.::..||..|.|.     :.|.....||
  Fly   357 QQMNSKGVGFARMESREKCEQIIQMFNGNTIPGAKDPLLVKFADGGPKK---------------- 405

Human   286 ERISRYQGVNLYIKNLDDTID-DEKLRKEFSPFG-SITSAKVMLEDGRSKGFG------FVCFSS 342
                         |||..|.| :.:..::.|..| .:.....|.::|.|...|      :..||:
  Fly   406 -------------KNLFKTPDPNARAWRDVSAEGIPVAYDPTMQQNGVSVNVGTPIGVPYSRFSA 457

Human   343 PEEATKAVTEMNGRIVGSKPLYVALAQ-------RKEERKAHLTNQYMQRVA----GMRALPANA 396
            |:             ||..|  ||.:|       .:.:.:...:.||||..|    |:.:....|
  Fly   458 PQ-------------VGGYP--VAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGVTSYKPEA 507

Human   397 ILNQFQPAAGGYFV---PAVPQAQGRP----------------PYYTP 425
            : ||.||......|   ..||.....|                |||.|
  Fly   508 V-NQVQPRGISMMVSGDTGVPYGTMMPQLATLQIGNSYISPTYPYYAP 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC4	NP_001129125.1	PABP-1234	11..640	CDD:130689	90/373 (24%)
shep	NP_001246636.1	RRM_SF	240..321	CDD:473069	26/93 (28%)
		RRM2_MSSP	322..400	CDD:409690	23/77 (30%)