Protein Alignment PABPC4 and CG12288

DIOPT Version :10

• Sequence 1: NP_001129125.1
• Gene: PABPC4 / 8761
• HGNCID: 8557
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_609822.1
• Gene: CG12288 / 35027
• FlyBaseID: FBgn0032620
• Length: 435
• Species: Drosophila melanogaster
• Alignment Length: 332
• Identity: 80/332 - (24%)
• Similarity: 129/332 - (38%)
• Gaps: 95/332 - (28%)

Human    11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLG----------------YAYVNF 59
            ::::||:|..:.....|.:.|.|.|.|.|||:       |:.|                .|||..
  Fly   155 STVFVGNLPINTKRVQLVKLFQPYGLVQSIRL-------RTAGGKQLFKHKQRKVAGSLNAYVVL 212

Human    60 QQPADAERALDTMNFDVIKGKPIRI----------MWSQRDPSLRKSGVGNVFIKNLDKSIDNKA 114
            ::|..|::|| .:|....|...:|:          ....:.|| .|.....:|:.:|..|...:.
  Fly   213 EKPEIAQQAL-ALNGSEFKENHLRVTPASMAEKFGQAKDKQPS-DKDAKRTIFVGSLKYSATEEQ 275

Human   115 LYDTFSAFGNILSCKVVCD-ENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKE 178
            |.:.||:.|.|...:.:.| :.|.||.|:|.|:..:|...|:| :|..||:||.:.|.|::.:|
  Fly   276 LREIFSSCGEIDYIRCLQDGDKGCKGVAYVCFQKPDAVGLALE-LNQTLLDDRPINVERYQVKK- 338

Human   179 REAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHED 243
                ||||              :|.|.:.....|:.......|     |..|.|
  Fly   339 ----LGAK--------------QVRDAAAASAASKTSSKTKAK-----NQNSAG----------- 369

Human   244 ANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDE 308
            |.|.:::..|||                 ...||::.....|::.|.|:||.:      |.|...
  Fly   370 AKKRLDKKKGKE-----------------NGSLKKEGAPTGQKKKSEYRGVKV------DGIKKA 411

Human   309 KLRKEFS 315
            |..|:.|
  Fly   412 KKPKKKS 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC4	NP_001129125.1	PABP-1234	11..640	CDD:130689	80/332 (24%)
CG12288	NP_609822.1	RRM1_RBM34	156..237	CDD:409828	23/88 (26%)
		RRM_SF	261..332	CDD:473069	23/71 (32%)