Protein Alignment PABPC4 and Spx

DIOPT Version :10

• Sequence 1: NP_001129125.1
• Gene: PABPC4 / 8761
• HGNCID: 8557
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_511058.1
• Gene: Spx / 31558
• FlyBaseID: FBgn0015818
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 183
• Identity: 72/183 - (39%)
• Similarity: 109/183 - (59%)
• Gaps: 7/183 - (3%)

Human    11 ASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFD 75
            |::|.|.|...|:|.:|:|.|..||||:::.:.:|.:|:...||.:|.|....||:..:..||..
  Fly    13 ATIYAGGLDDKVSETLLWELFVQAGPVVNVHMPKDRVTQMHQGYGFVEFLSEEDADYGIKIMNMI 77

Human    76 VIKGKPIRIMWSQRDPSLRKSGVG-NVFIKNLDKSIDNKALYDTFSAFGNILSC-KVVCD-ENG- 136
            .:.|||||:  ::.....:...|| |:||.|||..:|.|.|||||||||.||.. |::.| |.|
  Fly    78 KLYGKPIRV--NKASAHQKNLDVGANIFIGNLDVEVDEKLLYDTFSAFGVILQTPKIMRDPETGK 140

Human   137 SKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELGAKAKE 189
            ||.:||::|.:.||:|.|::.|||..|.:|.:.|. :..:|:.:.|....|.|
  Fly   141 SKSFAFINFASFEASDAAMDAMNGQYLCNRPISVS-YAFKKDHKGERHGSAAE 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PABPC4	NP_001129125.1	PABP-1234	11..640	CDD:130689	72/183 (39%)
Spx	NP_511058.1	RRM1_SF3B4	15..88	CDD:409771	27/74 (36%)
		RRM2_SF3B4	99..181	CDD:409772	39/82 (48%)