DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment B3GALT2 and brn

DIOPT Version :9

Sequence 1:	NP_003774.1	Gene:	B3GALT2 / 8707	HGNCID:	917	Length:	422	Species:	Homo sapiens
Sequence 2:	NP_476901.1	Gene:	brn / 31358	FlyBaseID:	FBgn0000221	Length:	325	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	82/293 - (27%)
Similarity:	148/293 - (50%)	Gaps:	42/293 - (14%)

- Green bases have known domain annotations that are detailed below.

Human   124 NEKGTGHPNS--YHFKYI----------INEPEKCQEKSPFLILLIAAEPGQIEARRAIRQTWGN 176
            ::.|:|..:|  ..|.|:          :::|.:       |.:||.:..|....|.|||:|||.
  Fly    46 DDTGSGSASSGLDKFAYLRVPSFTAEVPVDQPAR-------LTMLIKSAVGNSRRREAIRRTWGY 103

Human   177 ESLAPGIQITRIFLLGLSIKLNGYLQRAILEESRQYHDIIQQEYLDTYYNLTIKTLMGMNWVATY 241
            |.....:.:.|:||||.:..    .::.:..|||::.||:|.|:.|.|:|.|:||::||.|.:..
  Fly   104 EGRFSDVHLRRVFLLGTAED----SEKDVAWESREHGDILQAEFTDAYFNNTLKTMLGMRWASDQ 164

Human   242 CPHIPYVMKTDSDMFVNTEYLINKLL-------KPDLPPRHNYFTGYLMRGYAPNRNKDSKWYMP 299
            .....:.:..|.|.:|:.:.:: |.|       :|:|     .|.|::.: .:|.|:|.||||:.
  Fly   165 FNRSEFYLFVDDDYYVSAKNVL-KFLGRGRQSHQPEL-----LFAGHVFQ-TSPLRHKFSKWYVS 222

Human   300 PDLYPSERYPVFCSGTGYVFSGDLAEKIFKVSLGIRRLHLEDVYVGICLAKLRIDPVPPPNEFVF 364
            .:.||.:|:|.:.:...::.|.....:::..|:.:.....:|||:||...|..|. :...::|.|
  Fly   223 LEEYPFDRWPPYVTAGAFILSQKALRQLYAASVHLPLFRFDDVYLGIVALKAGIS-LQHCDDFRF 286

Human   365 NHWRVSYSS-CKYSHLITSHQF-QPSELIKYWN 395
            :  |.:|.. ..||.:|.||:| .|.|:.:.||
  Fly   287 H--RPAYKGPDSYSSVIASHEFGDPEEMTRVWN 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
B3GALT2	NP_003774.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	90..110
B3GALT2	NP_003774.1	Galactosyl_T	165..359	CDD:250845	58/200 (29%)
brn	NP_476901.1	Galactosyl_T	92..282	CDD:250845	58/201 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	1	1.000	-	-		FOG0000088
OrthoInspector	1	1.000	-	-		otm40700
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11214
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.850